MarketAntiparasitic
Company Profile

Antiparasitic

Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases, such as those caused by helminths, amoeba, ectoparasites, parasitic fungi, and protozoa, among others. Antiparasitics target the parasitic agents of the infections by destroying them or inhibiting their growth; they are usually effective against a limited number of parasites within a particular class. Antiparasitics are one of the antimicrobial drugs which include antibiotics that target bacteria, and antifungals that target fungi. They may be administered orally, intravenously or topically. Overuse or misuse of antiparasitics can lead to the development of antimicrobial resistance.

Types
Broad-spectrumNitazoxanide AntiprotozoalsMelarsoprol (for treatment of sleeping sickness caused by Trypanosoma brucei) • Eflornithine (for sleeping sickness) • Metronidazole (for vaginitis caused by Trichomonas) • Tinidazole (for intestinal infections caused by Giardia lamblia) • Miltefosine (for the treatment of visceral and cutaneous leishmaniasis, currently undergoing investigation for Chagas disease) Antihelminthic Antinematodes , attached to the intestinal mucosa. • Mebendazole (for most nematode infections) • Pyrantel pamoate (for most nematode infections) • Thiabendazole (for roundworm infections) • Diethylcarbamazine (for treatment of Lymphatic filariasis) • Ivermectin (for prevention of river blindness) • Fenbendazole AnticestodesNiclosamide (for tapeworm infections) • Praziquantel (for tapeworm infections) • Albendazole (broad spectrum) AntitrematodesPraziquantel AntiamoebicsRifampinAmphotericin B AntifungalsFumagillin (for microsporidiosis) ==Medical uses==
Medical uses
Antiparasitics treat parasitic diseases, which impact an estimated 2 billion people. ==Drug development history==
Drug development history
Early antiparasitics were ineffective, frequently toxic to patients, and difficult to administer due to the difficulty in distinguishing between the host and the parasite. Metal-containing compounds are the subject of another avenue of approach. ==Research==
Research
In the last decades, triazolopyrimidines and their metal complexes have been looked at as an alternative drug to the existing commercial antimonials, searching for a decrease in side effects and the development of parasite drug resistance. ==See also==
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