Various forms of aversion therapy have been used in the treatment of addiction to alcohol and other drugs since 1932 (discussed in
Principles of Addiction Medicine, Chapter 8, published by the
American Society of Addiction Medicine in 2003).
Alcohol addiction An approach to the treatment of
alcohol dependence that has been wrongly characterized as aversion therapy involves the use of
disulfiram, When a person drinks even a small amount of alcohol, disulfiram causes
sensitivity involving highly unpleasant reactions, which can be clinically severe. Rather than as an actual aversion therapy, the nastiness of the
disulfiram-alcohol reaction is deployed as a drinking deterrent for people receiving other forms of therapy who actively wish to be kept in a state of enforced sobriety (disulfiram is not administered to active drinkers). Another approach in creating aversions to alcohol consumption is the implementation of succinylcholine chloride-induced paralysis and respiratory arrest following exposure to alcohol. However, this method has not been found to be effective in emetic therapy or covert sensitization. Additionally, many patients reported a sense of fear and anxiety pertaining to dying as a result of the treatment, therefore this tactic is not recommended for therapeutic use. Other research using emetic-based aversion therapy combined with functional MRI observed reduced craving and changes in brain activation patterns related to alcohol cues. In a clinical follow-up of 100 individuals who received four sessions of chemical aversion therapy, 69% reported continued abstinence at 12 months. While some approaches have been criticized or mischaracterized, findings like these suggest that aversion-based methods—when properly implemented—may have therapeutic value for motivated patients.
Cocaine dependency Emetic (to induce
vomiting) therapy and faradic (
administered shock) aversion therapy have been used to induce aversion for cocaine dependency. When used in a
multimodal program, chemical aversion therapy displayed high patient acceptability among cocaine users as well as promising outcomes such as aversions to the sight, taste, and smell of the drug. Clinical studies have found that pairing cocaine-related cues with aversive stimuli can significantly reduce self-reported craving and physiological reactivity. In one controlled trial, patients undergoing chemical aversion therapy demonstrated conditioned responses of nausea when exposed to cocaine paraphernalia, suggesting the formation of drug-avoidant associations. Additionally, a neuroimaging study indicated that aversion-based interventions may reduce activity in reward-related brain regions during drug cue exposure, further supporting their potential use in relapse prevention. While more rigorous, large-scale trials are needed, early findings suggest aversive conditioning may play a useful role within comprehensive cocaine treatment programs.
Cigarette addiction It is unknown whether aversion therapy, in the form of rapid smoking (to provide an unpleasant stimulus), can help
tobacco smokers overcome the urge to smoke. Although in recent years, a new tactic in aversion therapy has been introduced specifically to individuals who struggle with nicotine addiction. A device, which is worn on the wrist of the user, holds a self administered electrical stimulus within it aimed at deterring the use of nicotine. Some research has examined the potential of aversive conditioning in smoking cessation programs. In controlled trials, rapid smoking—where individuals repeatedly inhale cigarettes to the point of discomfort has shown mixed results, with some studies reporting temporary reductions in cigarette craving and consumption. Additionally, randomized studies using electric shock as a form of contingent punishment have reported short-term decreases in smoking frequency, although ethical concerns and high dropout rates have limited widespread adoption. While these methods remain controversial and are not first-line treatments, they reflect ongoing efforts to pair nicotine use with unpleasant consequences in order to alter behavior. ==In compulsive habits==