Jalal’s research spans
neuroscience and
psychiatry, including the mechanisms underlying
perception,
consciousness, and
mental disorders. His work combines experimental and clinical research, and cross-cultural approaches to study sleep conditions and dream states,
hallucinations, anxiety-related conditions, and
obsessive–compulsive disorder. He has also contributed to research on human motivation and subjective experience, including studies on outcome uncertainty and
intrinsic motivation.
Sleep paralysis Sleep paralysis, is a condition in which individuals experience temporary paralysis upon waking or falling asleep, often accompanied by vivid hallucinations. Jalal has conducted studies exploring sleep paralysis in diverse populations, including samples from Egypt, Italy, Poland, Denmark, Turkey, the United States, and South Africa. Jalal's findings have highlighted how cultural beliefs shape the experience, interpretation, and distress associated with sleep paralysis. In a 2023 essay in TIME Magazine, he wrote: “Once sleep paralysis is feared as a mythical monster, anxiety runs amok, triggering unwanted awakenings at night and effectively more sleep paralysis. This vicious cycle perpetually feeds into itself until sleep paralysis becomes chronic, prolonged and potentially pathological.” Their theories explore the roles of the right superior parietal lobule, body image projection, mirror neurons, and the neuropharmacology of hallucinations. Jalal developed one of the first treatment approaches for sleep paralysis, known as Meditation-Relaxation Therapy (MR Therapy). The method combines cognitive reappraisal, emotional distancing, focused attention, and relaxation techniques to help manage recurrent episodes. In collaboration with researchers at the University of Bologna, he co-authored the first published clinical trial evaluating a treatment for sleep paralysis, which tested the MR Therapy approach.
Obsessive–compulsive disorder (OCD) In 2015 Jalal, working with
V. S. Ramachandran, conducted some of the first studies using the
rubber hand illusion to examine body image in
obsessive–compulsive disorder (OCD). They found that when a rubber hand was "contaminated" with fake feces during the illusion, healthy participants reported experiencing OCD-like disgust. In 2019, collaborating with
Richard J. McNally and
V. S. Ramachandran, Jalal showed that OCD patients were more susceptible to the illusion—even when visual and tactile cues were misaligned—suggesting a more flexible body image. This research also proposed the illusion as a form of indirect exposure therapy for OCD. In a 2017 study, Jalal and Ramachandran found that individuals with OCD symptoms experienced disgust simply by watching an experimenter contaminate themselves, and relief when watching them wash. In 2020, the findings were extended to a clinical OCD group with similar results. In later work with
Barbara Sahakian and Ramachandran, Jalal tested a digital self-observation technique in which participants with subclinical OCD watched daily smartphone videos of themselves touching fake feces or washing their hands. After one week, participants showed measurable improvements in symptoms. == Reception ==