After qualifying as a nurse, she went to work at the
Kent and Canterbury Hospital before returning to Scotland to take up the position of assistant matron at the
Simpson Memorial Maternity Pavilion in Edinburgh. In 1940 she moved to work at the 2,000-bed emergency war hospital,
Bangor Hospital near
Livingston. She was appointed
matron at the hospital, making her, at that time, the youngest woman in Scotland to hold such a position. In 1946, she was appointed matron of Glasgow Royal Infirmary, remaining there until 1955, after which she took up the position of lady superintendent of the
Royal Infirmary of Edinburgh. In the hospitals that Quaile oversaw, she implemented changes and efficiencies, including portering services to transport patients to and from wards rather than using nursing staff, actively encouraging the employment of male nurses, advocating for senior staff to live out from the hospital, and seeking improvements to nursing accommodation. Considered a strict disciplinarian with high standard, she was respected by both staff and patients. In 1958 she received an OBE for services to nursing. == Professional activities ==