The station was opened along with the rest of the line from 18 May 1939, by the which inaugural convoy would descend
Benito Mussolini, becoming however operation only since 20 July 1940 because of the need to complete several systems and the absence of the rolling stock. The 23 February 1958 was inaugurated the variant of track between
Candelo and
Biella that allowed him to leave the station to Piazza Vittorio Veneto, opened in 1856 and railway terminus Samthià–Biella railway, considered to be exceeded. The day after the station Biella San Paolo was the terminus of the lines to
Novara and
Santhià. From 21 January 1961, in advance to the end of the concession to the "Società Ferrovia Biella-Novara (SFBN)" company, the management of the railway line passed to the state and the exercise of the stations was assumed by
Ferrovie dello Stato. In the year 2000, the plant management passed to
Rete Ferroviaria Italiana, which is classified in the category "Silver". Recently, the station has been affected by modernization works for the deployment of an ACEI train control system, the lengthening of station platforms, and the construction of a railway bridge serving tracks 2-3-4. About €7 million was spent, jointly funded by RFI and the
Region of Piedmont. In September 2008, a local health unit analysis had revealed small amounts of
asbestos, originating from
Balangero in the 1970s, in some stones at the station, but this was though not to cause particular danger to the health of travelers and workers. ==Features==