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Ed "Big Ed" Burns (c. 1842–?), American con man and crime boss •
Ed Delahanty (1867–1903), American Major League Baseball player •
Ed Reulbach (1882–1961), American Major League Baseball pitcher •
Ed Sanders (boxer) (1930–1954), American boxer and 1952 Olympic heavyweight champion •
Edward Everett Smith (1861–1931), Lieutenant Governor of Minnesota •
Ed Stevens (baseball) (1925–2012), American Major League Baseball player •
Ed Walsh (1881–1959), American Major League Baseball pitcher and manager •
Ed White (American football) (born 1947), American former National Football League player ==Stage name==