At
George H. W. Bush State Prison somewhere in the
Southwestern United States, William "Bill" Boss, a
cannibalistic,
psychopathic warden, watches the end of
The Human Centipede 2 (Full Sequence) with his accountant, Dwight Butler. Bill is then informed that one of the guards has been injured. He then confronts and breaks the arms of the inmate who did it. He then goes outside and yells at the rest of the inmates. Bill receives a threatening prank phone call from an inmate. He then has a medical checkup with Dr. Jones in which Bill believes there is nothing wrong with himself. Bill
waterboards the inmate who prank called him with three buckets of boiling water as punishment, horribly disfiguring him. Governor Hughes arrives, ordering Bill and Dwight to put a stop to the violence and promising that they will both be fired otherwise. In anger and retaliation, Bill orders a mass
castration of the inmates, brutally castrating one of the prisoners himself, then cooks and eats the testicles for "energy food." Dwight pitches an idea to fix the prison's horrible retention and violence rates to Bill: suture all of the inmates together mouth-to-anus, forming a giant human centipede, which would be the ultimate deterrent to crime. Bill is skeptical and opposed to the idea. Bill then has a nightmare about being attacked by inmates, and raped by the inmate he castrated. Bill then summons the director of
The Human Centipede 2,
Tom Six, to the prison. Bill is assured that the films are "
100% medically accurate". Six gives the prison permission to use his Centipede idea, provided that he is permitted to witness the operation. The first two films are then shown to the inmates as a display of their future, which causes a riot. Inmates chase Bill and Dwight to the warden's office, resulting in Dwight ordering the entry of special forces. The rioting prisoners beat his assistant Daisy unconscious until they are subdued by the assault team, which restore order in the prison. Bill goes around each cell and shoots every inmate with tranquilizers, readying them for the operation. Incompatible inmates are shot and killed. They discover an inmate with
Crohn's disease, who suffers from severe
diarrhea. Bill orders the man who raped him in the dream to be attached to him as an added punishment. Daisy is in a coma, where she is raped by Bill. Six returns to the prison, where he is met by Bill and Dwight. After touring the cells, they discover a mentally unstable inmate eating his own feces wanting to be sewn to the centipede. Bill shoots and kills the inmate as he does not want anyone to enjoy the punishment. Upon the centipede's completion, Governor Hughes arrives greatly disgusted at what he sees. In addition to the centipede, a "Human Caterpillar" has been created by suturing together death row inmates, along with those who were given a life sentence, and amputating their limbs. Daisy has been sewn into the Centipede while one inmate from the Centipede is in the infirmary, having been disconnected because he served his time. Hughes leaves the prison, telling Dwight and Bill they should receive the
death penalty. In anger, Bill shoots Dr. Jones dead. However, Hughes returns to prison with a sudden change of heart, stating that the Centipede punishment is "exactly what America needs." After Hughes leaves, Dwight and Bill celebrate their success. Dwight is then shot and killed by Bill for trying to take credit for the idea. In the final scene, a naked Bill screams with joy in the lookout tower overlooking the Centipede while
the Star-Spangled Banner plays.
Alternate ending In an alternate ending, Doctor Josef Heiter lies in his bed, implying that the previous events were part of a dream. He finds his three
rottweilers, his first centipede creation, deceased. The camera pans over his house and the film transitions into the beginning of
The Human Centipede (First Sequence). ==Cast==