After completing his dissertation, Zemelman began working in the laboratory of
James Rothman on SNARE proteins and their influence on the intracellular membrane fusion. Subsequently, Zemelman worked jointly with
Gero Miesenböck to perform seminal experiments in 2002 and 2003 on selective stimulation of neurons using light, a field that came to be known as
optogenetics. These techniques were later improved by
Karl Deisseroth in 2005; these pioneering studies in optogenetics led to these three scientists being regarded as candidates for the Nobel Prize in 2013. In 2015 Zemelman and his colleagues received three grants totaling $4 million, to develop techniques for imaging and manipulating the activity of neurons in the brain. The grants were made through
Barack Obama's Brain Research through Advancing Innovative Neurotechnologies (BRAIN) initiative launched in 2014. ==References==