Moe notices tension in the marriages of
Homer,
Apu, and
Reverend Lovejoy.
Mother's Day is approaching, and
Marge, needing a break, suggests Homer take the children to Weasel Island after
Krusty promotes it. Homer is enthusiastic but becomes concerned when Marge mentions his leaving will allow her to take care of an errand. As the ferry to the island departs, the three men receive a letter from Moe saying he is running off with one of their wives. At Weasel Island, Homer, Apu and Lovejoy agonize over their situation. Each insists their marriage is fine. Homer, however, remembers his mother-in-law's 80th birthday, where Moe was the bartender. Homer, who was angry at Marge for only serving non-alcoholic beer, got into an argument with
Patty and Selma. Disgusted, Homer drove them out, and Marge told him that he ruins every event she plans. Apu notices cracks in his marriage, recollecting an incident where he and
Manjula forgot their son at Moe's after using the bar's bathroom. Manjula went to retrieve their son and did not return for hours. Homer recalls seeing Manjula playing a video game with Moe that night. Lovejoy remembers advice given to him that he ignored his wife
Helen's needs, and Apu recounts how he witnessed Moe confiding in Helen that he was in love with a married woman. When the ferry returns to the mainland, they realize they are equally likely to have lost their wives to Moe. At home, Homer thinks Marge is packing a suitcase and tries to convince her to stay. He realizes that she has painted a portrait of her mother.
Jacqueline assures Homer that he was not responsible for the birthday incident. She admits that it was Patty and Selma's fault. When Lovejoy arrives home, he too thinks Helen is leaving, but she surprises him with tickets to
Istanbul on board the
Orient Express. Apu arrives home to find Moe sitting with Manjula, but she tells Apu that he convinced her to salvage their marriage. Moe reveals he saw how troubling the relationships were, so he organized Marge's portrait, the Lovejoys' trip, and the Nahasapeemapetilons' marriage rescue. He wrote the letter to teach the men a lesson about taking their wives for granted, saying that they need to value them more. Upon learning this, Homer thanks Moe. In the end, Moe implores viewers to value their wives and mothers this Mother's Day. ==Cultural references==