Wyles' first professional club was the championship team,
Nottingham RFC. He then played for
Northampton Saints, in the 2006-2007 season, when he caught the eye of the
USA Eagles coaching team, which led to his involvement in the
IRB Sevens World Series and the
2007 Rugby World Cup in France. Wyles joined
Saracens in summer of 2008, after impressive performances in the
2007 Rugby World Cup.
Eddie Jones, who was on the Springboks coaching team, saw Wyles' potential and when Jones became Director of Rugby at
Saracens, he brought him to the club. Wyles debuted for Saracens on 12 September 2008 against the Sale Sharks. In the 2009-2010 season he was a regular starter on the wing, playing in the Saracens team that took on
Leicester in the final of the
English Premiership. For his performances during the 2009/10 season, Wyles was nominated for Player of the Season by
Brendan Venter. Following on from that season, Wyles became a key figure in the successful 2010-11 Premiership winning side, beating Leicester 22-18 in the Final. In the 2014-15 season, Wyles scored 12 tries, tying for second-highest scorer in the English Premiership. One of these tries helped Saracens to a second Premiership title by defeating Bath 28-16 in the final. In the 2015-2016 season, Saracens won the Premiership Title for a third time, defeating Exeter 28-20. Wyles scored in the final for the second year running, and won the European Champions Cup, 21-9, against Racing 92. In the 2016-17 season, Saracens won the European Championship for a second year in a row, defeathig Clermont Auvergne 28-17, in Edinburgh. Wyles made his 50th European appearance during this season. Wyles has contributed over 60 tries for his club with 23 of them scored in European Competition. As of the 2017-18 season, Wyles holds the record for most tries scored in the Premiership semifinal rounds with five. Wyles went on to score two tries in the final as Saracens claimed their fourth Premiership title in eight years with a 27-10 win over Exeter at Twickenham; these were his third and fourth tries scored in a victorious Premiership final after getting one in 2015 and one in 2016. Wyles retired in 2018. He then began working for Wolfpack lager, with former team-mate
Alistair Hargreaves. ==International career==