Nunes made her professional debut in 2010 competing in regional promotions, and amassed a record of 5–3 before joining
Invicta FC.
Invicta FC Nunes made her promotional debut against
Munah Holland on December 7, 2013, at
Invicta FC 7. Nunes won the fight via TKO in the third round and earned the
Knockout of the Night bonus award. Nunes lost the fight via unanimous decision. Nunes was expected to face
Rose Namajunas on May 23, 2015, at
UFC 187. After having made no attempts to cut further, she was fined 20 percent of her fight purse, which went to Namajunas. Nunes next faced
Justine Kish at
UFC 195 on January 2, 2016. She lost the fight by unanimous decision. Nunes faced
Jocelyn Jones-Lybarger at
UFC Fight Night: Rodríguez vs. Penn on January 15, 2017. She won the fight via submission in the third round. Nunes faced
Angela Hill at
UFC Fight Night: Poirier vs. Pettis on November 11, 2017. She won the fight via unanimous decision. Nunes faced
Randa Markos on July 28, 2018, at
UFC on Fox: Alvarez vs. Poirier 2. She won the fight by unanimous decision. Nunes faced
Cláudia Gadelha on December 8, 2018, at
UFC 231. She won the fight via unanimous decision. Nunes faced
Tatiana Suarez on June 8, 2019, at
UFC 238. She lost the fight via unanimous decision. On October 10, 2019, Nunes announced that she would put her mixed martial arts career on hold in order to attempt to have her first child. The attempts were successful as in March 2020, her wife Amanda Nunes announced that the couple is expecting their first child, to be born later that year. Nina Nunes gave birth to a daughter in September 2020. Nunes faced
Mackenzie Dern on April 10, 2021, at
UFC on ABC 2. She lost the bout via first round armbar. Nunes was scheduled to face
Amanda Lemos on December 18, 2021, at
UFC Fight Night 199. However, Nunes was removed from the bout for undisclosed reason and she was replaced by
Angela Hill.
Move up to flyweight division Nunes was scheduled to face
Cynthia Calvillo in a flyweight bout on July 9, 2022, at
UFC on ESPN 39. However, the day of the event, Nunes withdrew due to illness and the bout was initially cancelled, but eventually rescheduled for
UFC on ESPN 41 on August 13, 2022. Nunes won the fight via split decision, and she announced her retirement after the fight. == Personal life ==