Costochondritis is predominately a
clinical diagnosis only after life-threatening conditions have been ruled out, with physical examination and medical history being considered. Before a costochondritis diagnosis is made, other serious causes of chest pain are investigated. Further evaluation for
cardiopulmonary or
neoplastic causes is typically based on history, age, and
risk factors, with diagnostic imaging and tests, completed to assess for life-threatening emergencies. If there is a suspicion of infection or a
rheumatoid condition,
laboratory work may be conducted. A physical exam will assess for tenderness or pain upon
palpation, with an absence of heat,
erythema, or swelling. The physical exam may assess if the pain is worsened with movements of the upper body or breathing, and may be reproduced upon using the crowing rooster maneuver, the hooking maneuver, or the horizontal flexion maneuver. Medical history is considered in diagnosing costochondritis, such as inquiry regarding any recent trauma, coughing, exercise, or activity involving the upper body that may have caused the symptoms.
Differential diagnosis Cardiopulmonary Life-threatening medical emergencies that may be associated with chest wall pain include
acute coronary syndrome,
aortic dissection,
pneumothorax, or
pulmonary embolism. Other cardiopulmonary causes of
chest pain similar to that produced by costochondritis may include but are not limited to
myocardial infarction,
angina, and
pericarditis. With costochondritis, the pain is typically worse with respiration, with movement, or within certain positions. Typically with other causes of chest pain, individuals will likely have radiating pain, shortness of breath, fever, a productive cough, nausea, dizziness, tachycardia, or hypotension. A similar condition known as
slipping rib syndrome is also associated with chest pain and inflammation of the
costal cartilage. Unlike costochondritis, the pain associated with slipping rib syndrome is often felt in the lower ribs, abdomen, and back, commonly affecting the
interchondral junctions of the
false 8th to 10th ribs. Costochondritis is typically experienced within the
sternocostal junctions of the
true 2nd to 5th ribs. Other musculoskeletal conditions that may cause chest pain similar to costochondritis includes but are not limited to, painful
xiphoid syndrome,
muscle strain,
myofascial pain syndrome,
thoracic disk herniation, and
rib fracture.
Other •
Rheumatologic conditions such as
fibromyalgia,
SAPHO syndrome,
ankylosing spondylitis,
rheumatoid arthritis, and
psoriatic arthritis can cause symptoms similar to costochondritis. • Chest pain is occasionally experienced with
respiratory-related conditions such as
pleuritis,
precordial catch syndrome, and
pneumonia. • Some
gastroenterology conditions may be associated with costochondritis-like chest pain such as
gastroesophageal reflux disease, and
esophagitis. ==Outlook, treatment and prevention==