In 1946, he won 1st place in weightlifting at the XII Olympic Sports Event of India held in Bangalore, for the heavyweight class. He annexed Kerala title in 1942 and the Bombay provincial honours in 1944 breaking all the previous records. He represented India in International competitions held in
Burma in 1947. He won gold medal in Indian Olympic Sports Event held at Delhi in 1952. He lifted 780 pounds in the Heavyweight Category. In 1954 Indian Olympic Sports Event he won Gold medal again and established three records. Rajagopal was the 1st Indian Weightlifting Champion and held the title continuously for 13 years from 1945 to 1958. He won Mr. Asia title in 1948 at Calcutta at the Asian bodybuilding competition. He won a bronze medal in
1951 Asian Games in men's heavyweight (+90 kg) weightlifting which remains one of the best performances by an Indian weightlifter considering the strong field of countries participating. Rajagopal represented India thrice at the
Olympics, in
1948 (finishing
16th),
1952 (finishing
6th) and
1956 (finishing
9th). He was the founder and first President of Andhra Olympic Association. He was the captain of Andhra Olympic team. He helped found several other sports associations in Andhra Pradesh.
Kamineni Eswara Rao was trained by Dandamudi in weightlifting. He established free gymnasia named Dandamudi Rajagopal Institutes, at locations across Krishna district to coach youngsters. ==Honours and popularity==