Rose was involved in the early development of the
Silicon Alley technology community in New York, including working with pre-Internet era online data services and founding Ex Machina, a computer software company; The Computer Classroom, an early personal computer training company; and AirMedia, an early wireless Internet information network. Rose founded and runs a technology incubator in New York City and is a founding member of the Space Angels Network, an international investing group. In 2005,
BusinessWeek magazine included an article titled 'The Pitch Coach' about his sessions for entrepreneurs seeking funding from venture capitalists and angel investors. He is an Associate Founder of
Singularity University, the post-graduate program in accelerating technologies, and founded and chaired its Finance, Entrepreneurship and Economics track. In 2025, Rose participated in public events with futurist
Ray Kurzweil on the implications of AI and the coming technological singularity. In 2025, Rose publish his new book
The Singularity Is Nearer: When We Merge with AI. ==Personal life==