At the Maudsley, Shaffer conducted the first epidemiological study of child and early adolescent suicide using the
psychological autopsy method. He found that there was a short delay between experiencing a stressor and the act of suicide, youth tended to show elevated levels of aggressive behavior prior to committing suicide, and imitation appeared to play a role in youth suicide. These findings would later be confirmed in his much larger controlled study in New York City and the surrounding area. Other important findings from the New York study included the very high prevalence of alcohol and
substance abuse in older male teens who committed suicide and the occurrence of a prior suicide attempt as a predictor of suicide in males, but not females. In females,
major depression was especially important predictor of suicide. This stimulated the development of a screening strategy instead. Ultimately, Shaffer led a team of colleagues in creating the Columbia
TeenScreen. The scoring algorithm had a
sensitivity of 0.75,
specificity 0.83, and
positive predictive value 16% with suicidal ideation as the criterion. Other research interests included the development of diagnostic instruments. He was charged by the
National Institutes of Health (NIMH) to develop a child version of the Diagnostic Interview Schedule (DIS) for use in large field studies. The NIMH DISC "is a highly structured diagnostic interview, designed to assess more than 30 psychiatric disorders occurring in children and adolescents, and can be administered by "lay" interviewers after a minimal training period." Shaffer led the development of several editions of the DISC, including the version (NIMH DISC-IV), which is based closely on
DSM-IV. == Other research ==