Main characters • Eugenia P. Kisskillya (voiced by
Kathleen Freeman) – The gym teacher and detention warden of Benedict Arnold Middle School. Having been a military
sergeant in the
United States Marine Corps, Miss Kisskillya bosses the children around like such, calls other people by
military rankings, bringing up some moments of her military past, and usually pronounces "detention" as "dee-tennnn-shun!!". Despite usually being
tyrannical towards the children, she has been shown to be a nice person. She is based on the creator's grade schoolteacher who was a
nun, as well as Freeman's character, the strict Sister Mary Stigmata, from
The Blues Brothers and
Blues Brothers 2000. • Shareena Wickett (voiced by
Tara Charendoff) – A
gothic 12-year-old girl that prefers to be a free spirit and finds pleasure in the sublime. Shareena's beliefs are never taken seriously by her parents. Her hobbies include reading
horror fiction stories. She has a talent for
séances. • Pig - Shareena's pet pig. While originally thought to be a male pig, it was discovered that Pig is actually a female pig in "The Blame Game". • Shelley Kelly (voiced by
Pamelyn Ferdin) – An
optimistic and peppy girl who wears the same Ladybug Scout uniform and the only kid in detention not due to rule breaking, but because she is a
teacher's pet to Ms. Kisskillya as she refers to Shelley as "
Private Kelly". She is constantly
kissing up to Miss Kisskillya and has a crush on Emmitt. As a result, she is often detested by the other kids who she wishes to be friends with (she seems to have succeeded with Shareena to an extent). However on some occasions, Shelley is an ally to the other kids. • Emmitt Roswell (voiced by
Billy West) – A
conspiracy theorist and
ufologist who explains that intelligent
extraterrestrial life exists in
outer space. He is determined to make contact with aliens. As stated in "Boyz 'N the Parenthood", Emmitt has an estranged father. • Jim Kim (voiced by the series' writer Roger Eschbacher) – A shy kid with a love for
comic books, particularly from
DC Comics. He takes on the characters' attributes at inopportune times. • Ramone "Gug" Gugliamo (voiced by
Carlos Alazraqui) – A short Latino kid with a short temper. Constantly left out of competitive sports, Gug constantly picks fights with kids twice his own size and has even wanted to take down Miss Kisskillya. He and Emmitt have their occasional rivalries. However, they both agree on their lack of patience with Jim. • Duncan Bubble – A quiet boy who is always playing with a
yo-yo and not speaking. He instead uses his yo-yo to spell out messages (for example, "Thanks guys", "Boring", and "Yeah") accompanied by an electronic voice (done by the show's creator Bob Doucette) reading the message. He is based on a deaf friend Doucette (the show's creator) had during production. • Lemonjella and Orangejella LaBelle (voiced by
Tia Mowry and
Tamera Mowry) – A pair of identical
African-American twins. They have been known to get themselves in trouble by
hacking into the school computers and removing library fines. Their scientific descriptions tend to confuse Miss Kisskillya and the other kids, so they would simplify them to make sense. Lemonjella and Orangejella have shown to be competitive with each other.
Recurring characters • Patsy Wickett (voiced by
Mary Gross) - The mother of Shareena. • Mr. Fletcher (voiced by Bob Doucette) - The science teacher at Benedict Arnold Middle School. ==Broadcast and home media==