Strong's first professional role was Gracie in Limelight Theater's production of
The Music Man at the age of 13. and continued acting in both animated and live-action shows and films, before moving to Los Angeles in January 1994. Strong is the voice of numerous animated characters, including main roles in
The New Batman Adventures as
Barbara Gordon/Batgirl,
Teen Titans and
Teen Titans Go! as
Raven;
Fillmore! as Ingrid Third;
The Fairly OddParents as
Timmy Turner (Strong took over the role after the suicide of the original voice actress
Mary Kay Bergman—the two were close friends) and
Poof;
Rugrats and
All Grown Up! as
Dil Pickles;
The Powerpuff Girls as
Bubbles;
Ben 10 as
Ben Tennyson, Upgrade, Blitzwolfer, and Buzzshock;
Chowder as Truffles; ''
Foster's Home for Imaginary Friends as Terrence; the singing voice of Meg Griffin and additional voices on Family Guy; My Little Pony: Friendship Is Magic as Twilight Sparkle, Unikitty! as the titular princess, Wow! Wow! Wubbzy! as Daizy, and Dorothy and the Wizard of Oz'' as Joanni. While recording lines for her role as Dil in
Rugrats, one scene's script for Strong's character prompted her to make crying noises. During the taping, the producers suddenly paused and revealed to Strong that her voice acting of a child had been so realistic that she had inadvertently made a woman in the studio lactate. As the role was otherwise going to be offered to
Madonna, Strong subsequently quipped that she was proud that the incident led to her keeping the role. She has also lent her voice to English-dubbed
localizations of Japanese anime such as
Spirited Away and
Princess Mononoke, as well as several video games, including her work as Elisa and Ursula in
Metal Gear Solid: Portable Ops; Paz Ortega Andrade in
Metal Gear Solid: Peace Walker,
Metal Gear Solid V: Ground Zeroes, and
Metal Gear Solid V: The Phantom Pain;
Rikku in
Final Fantasy X, its sequel
Final Fantasy X-2, and
Kingdom Hearts II; Krista Sparks in
Twisted Metal: Head-On; Talwyn Apogee in
Ratchet & Clank Future: Tools of Destruction and its sequel,
Ratchet & Clank Future: Quest for Booty; Keira in
Jak and Daxter series; and
Juliet Starling, the main character of
Lollipop Chainsaw. She also has a minor voiceover for the teddy bear Ted in the motion picture
Ted. In
Blue Dragon, she is the voice actress for Kluke for the Xbox 360 game, but not in the
anime series. Beginning with the video game
Batman: Arkham City, Strong would also succeed
Arleen Sorkin as the voice of
Harley Quinn. She has appeared in live roles in ''
National Lampoon's Senior Trip, Sabrina Goes to Rome, Sabrina Down Under, and The Last White Dishwasher
. She also made guest appearances on such shows as Forever Knight, Street Legal, Touched by an Angel, Take Home Chef, Party of Five, Comic Book: The Movie, Kung Fu: The Legend Continues, 3rd Rock from the Sun and The Drew Carey Show''. In January 2013, she voiced the character Plum in
Cartoon Hangover's
Bravest Warriors, created by
Pendleton Ward. She recurred as Miss Collins in
Nickelodeon's live-action series
Big Time Rush from 2010 to 2013. In
2004, she won an
Interactive Achievement Award for her role as Rikku in
Final Fantasy X-2. She also served as the announcer for the
1999 Kids' Choice Awards, appeared as a guest panelist at several
fan conventions (including
BotCon, Jacon,
Comic-Con International, and
Anime Overdose), and was featured on the front cover of the July/August 2004 issue of
Working Mother magazine, in which she said, "My son is now old enough to respond to my work. To me, that's what it is all about." Strong has been nominated five times for
Annie Awards. In 2013, Strong won the
Shorty Award for "Best Actress" for her use of social media. The Behind the Voice Actors website selected her for a BTVA Voice Acting Award for Voice Actress of the Year for 2013, having nominated her for 2011 and 2012. Strong starred in the Canadian series
Pretty Hard Cases as Tiggy Sullivan, the head of a drug trafficking gang. She also voiced
Miss Minutes in the live-action
Marvel Cinematic Universe series
Loki. In
2006, Strong was unsuccessfully nominated for a
Daytime Emmy for Outstanding Performer in an Animated Program for her role as Dannan in
Jakers! The Adventures of Piggley Winks. == Activism ==