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Diane McBain (1941–2022), American actress •
Ed McBain (1926–2005), American author and screenwriter •
Edward McBain (died c. 1930), Scottish footballer •
Jack McBain (born 2000), Canadian ice hockey player •
James William McBain (1882–1953), Canadian chemist •
Jamie McBain (born 1988), American ice hockey player •
Laurie McBain (born 1949), American writer •
Laurie McBain (footballer) (1907–1937), Scottish footballer •
Lynn McBain, professor of general practice in New Zealand •
Roy McBain (born 1974), Scottish footballer •
Scott McBain (born 1960), Scottish fiction author ==In arts and entertainment==