San Luis held the position of
Mayor of Santa Cruz, Laguna, serving from June 30, 2019 until June 30, 2025.
Elections 2019 On October 16, 2019, San Luis filed his Certificate of Candidacy (COC) for
Mayor before the
COMELEC office in
Santa Cruz, Laguna. He ran under the
Nacionalista Party, with term-limited
Mayor Domingo G. Panganiban as his running-mate and formed their own slate, Team Egay-Dennis. On May 13, 2019, the elections were held and on the same day, he was proclaimed as
Mayor–elect beating incumbent
Board Member Benjo Agarao and former
Mayor Ariel Magcalas. San Luis garnered 48.09% of the votes to 45.16% of Agarao and in distant third, Magcalas with 6.75%.
2022 On October 5, 2021, San Luis filed his Certificate of Candidacy (COC) under
Aksyon Demokratiko for re-election in
COMELEC Santa Cruz office. He formed his new slate with incumbent Councilor Louie De Leon as his running-mate. On February 11, 2022, San Luis endorsed the
campaign of
Manila Mayor Isko Moreno for the
presidency with other local candidates. On May 9, 2022, the elections were held and on May 10, he was officially proclaimed for his second term in office, after garnering 50.97% of the votes to 49.03% of his sole opponent
Benjamin Agarao Jr., incumbent Representative.
2025 On October 2, 2024, San Luis filed his Certificate of Candidacy (COC) under the
National Unity Party for his third and final term in the new
COMELEC Santa Cruz office, located in Metro Central Mall. This time, his running-mate is Laura Obligacion,
ex officio Councilor for
Liga ng mga Barangay. The campaign trial was heated and on May 12, the elections were held and eventually, San Luis would be defeated by incumbent (Senior)
Board Member Benjo Agarao in a rematch, he obtained 47.54% of the votes to Agarao's 52.46%. The next day, San Luis thanked his supporters and conceded the election.
Mayoral Tenure San Luis took office on June 30, 2019 succeeding outgoing
Mayor Domingo G. Panganiban. His first term was seen as a fresh leadership in
Santa Cruz. During his first term the town's water provider was a problem and was replaced with
PrimeWater, a water and
wastewater services provider owned by the
Villar family. This resulted in controversies due to its failed services not only in
Santa Cruz, but in other places where it is the main service provider. On May 19, 2025, after a five-year contract with the company, San Luis announced that the town's water district finalized a decision to end their contract with
PrimeWater due to its failed services. During San Luis' term, the town faced major crisis's, especially when the
COVID-19 virus erupted which resulted in government placing the country in a
lockdown. Unemployment was high, the town's economy was primarily hit by the
pandemic. San Luis acted immediately and launched his program, the Kabuhayanihan. After losing the election, he once again faced major problem when part of the town's
public market was burned down on May 23, 2025. This resulted in many business establishments left destroyed by the fire. San Luis assures assistance for those market vendors whose affected by the fire, respectively. On June 18, 2025, San Luis suspended the classes from both
public and
private schools, and the work in the municipal hall and office after an anonymous person posted a
bomb threat online threatening the town schools and government offices. Later the threat was confirmed as hoax and the assailant was arrested by the authorities, respectively. Despite all of these events, during San Luis' leadership the town was awarded with the Seal of Good Local Governance (SGLG) from the
Department of Interior and Local Government (DILG) in 2019. The town was also awarded with Good Financial Housekeeping Award in 2019, 2021, 2022, 2023, and lastly in 2024, before his tenure ends. == Personal life ==