Beginning in 1963, she worked for the
University of Alaska Fairbanks, teaching Iñupiaq and developing their first degree programs in
Eskimo languages. She became tenured and was an associate professor at UAF until 1987. Throughout the 1970s and 1980s, she wrote, edited and published dozens of Iñupiaq language materials, including an abridged Iñupiaq dictionary in 1981 and an Iñupiaq grammar in 1986. She worked for the
State of Alaska Department of Education as a Special Assistant for Rural and Alaska Native Education to the Commissioner of Education from 1987 to 1990. In 1995, MacLean became president of
Iḷisaġvik College, leading Alaska's only nationally certified tribal college. She was succeeded by
Beverly Patkotak Grinage in 2005. In the 2000s, she spent two years working on a
Rosetta Stone software program in the North Slope dialect of Iñupiaq. After 30 years of work on the project, she finished the exhaustive Iñupiaq–English dictionary in 2014. She retired in 2014 and continues to contribute to Iñupiaq language projects in Alaska, serving on the
North Slope Borough's Iñupiaq History, Language, and Culture Commission. ==Awards and recognition==