•
1,2-Ethanedithiol, compound commonly used for cleavage during peptide synthesis •
EDT (Digital), text editor for PDP-11 and VAX/VMS computer systems •
EDT (Univac), text editor for UNIVAC Series 90 and Fujitsu BS2000 computer systems •
Electrodynamic tether, a spacecraft component •
Event dispatching thread, in Java == Time zones ==