From 1961 to 1966, he starred in the sitcom
Marriage Lines with
Richard Briers and
Prunella Scales. De Souza had roles in the
Hammer films
The Phantom of the Opera and
Kiss of the Vampire (both 1962). In the same year, he appeared in "Six Hands Across the Table", an episode of the British television series
The Avengers. De Souza appeared as the lead character, space security agent Marc Cory, in the
Doctor Who story "
Mission to the Unknown" (1965) – the only story ever broadcast in the series not to feature
the Doctor in any capacity. Since
David Graham's death in 2024, De Souza is the last surviving credited cast member of the serial. In 1967 he joined the BBC oil industry drama
The Troubleshooters as Charles Grandmercy. In 1977, he played Sheik Hosein in the
James Bond film The Spy Who Loved Me. He was solicitor Bonny Bernard in the first series of
Rumpole of the Bailey (1978). In the same year, he appeared in "Hearts and Minds", the last episode of
The Sweeney to be filmed, which featured the popular comedians
Morecambe and Wise. In 1982, he appeared in the final
Sapphire & Steel adventure as "The Man". He appeared in
Edward the Seventh (1975),
After Henry (1989–1990), and
Farrington. He had a cameo as
Lord Boreal / second high councillor in the 2007 fantasy film
The Golden Compass. In succession to
Valentine Dyall, the originator of the role, he was
The Man in Black on
BBC Radio 4 between 1988 and 1992. In 1993, De Souza played the role of Afonso in the
One Foot in the Grave special
One Foot in the Algarve. He joined the British soap opera
Coronation Street as
Colin Grimshaw, making his first appearance on 12 December 2008. His character died in May 2009. == Selected filmography ==