In 2013, Sifuna became a member of
CORD as a Technical/Advisory Committee Member for three years before joining
NASA in the same capacity. In the
2017 Kenyan general election, Edwin Sifuna expressed his interest to vie for the
Kanduyi Constituency Member of Parliament seat on an
ODM Party ticket. He was, however, not successful during the primaries in April where he lost to
John Makali. With only about two months to the general elections in August,
ODM fronted Sifuna as their preferred candidate to contest the Nairobi senatorial seat then held by
Mike Sonko. He polled 674,056 votes (42.51%) against winner
Johnson Sakaja who got 811,826 votes (51.20%). On 23 February 2018, Sifuna was picked as the Secretary-General of ODM party to replace
Ababu Namwamba. On 11 February 2026, he was removed as Secretary General by the National Executive Committee (NEC) in absentia. Sifuna petitioned to the Political Parties Disputes Tribunal (PPDT), which on 12 February, ruled to temporarily prevent the Orange Democratic Movement from executing his removal. In 2019, he was elected to serve as the vice-chair of the Centre for Multiparty Democracy (CMD).
Senate In the
2022 Kenyan general election, Sifuna once again contested the Nairobi Senatorial seat. He garnered 716,876 to clinch the seat and is now serving the people of
Nairobi as their senator. In February 2023, he assumed the role of deputy minority whip in the Senate. ==Personal life==