Chamberlain was born on November 5, 1867, in
Warsaw, New York. Moving to Buffalo as a child, Chamberlain began to play organized baseball as a teenager. His early professional career included stints with a minor league team in
Hamilton, Ontario, and with a
Southern League team in
Macon, Georgia. As a 17-year-old pitcher with Hamilton, he earned 18 wins and led the league in
strikeouts. Chamberlain made his major league debut with the
Louisville Colonels of the
American Association on September 13, 1886. In early October, Chamberlain was pitching in a game against the
Baltimore Orioles when Louisville players began to complain opposing pitcher
Matt Kilroy was leaving the pitcher's box when he threw the ball. When the umpire did not respond to Louisville's complaints, Chamberlain's manager told him to run forward out of the box when he let go of his pitches. The move "scared the Baltimore batters out of their wits" and Kilroy did not deliver any more questionable pitches. In 1887, Chamberlain won 18 games for Louisville. The right-hander, who stood and weighed 168 lbs., earned the nickname "Ice Box". Some sources attribute the nickname to his ability to remain cool when facing tough opposition, On May 9, 1888, while pitching against the
Kansas City Cowboys, Chamberlain pitched righthanded for the first seven innings and lefthanded for the last two innings. Louisville won the game by a score of 18–6. Chamberlain was traded to the
St. Louis Browns in August 1888, having already registered 14 wins for the Colonels that year. He earned 11 more wins in the last six weeks of the season. The series was Chamberlain's last major league postseason playing appearance. ==Middle career==