Fearon joined the
University of Michigan (U-M) in 1995 as the associate director for Basic Science Research at the University of Michigan Rogel Cancer Center. In 1999, Fearon was elected a Fellow of the
American Society for Clinical Investigation (ASCI). He later served as president of the ASCI from 2005 to 2006. During his tenure at U-M, Fearon's laboratory conducts research to understand how defects in cancer genes contribute to the development and progression of colorectal and other cancers. By 2013, he also served as the division chief of Molecular Medicine & Genetics in the Department of
Internal Medicine and co-directed the U-M Cancer Center's Cancer Genetics Research Program. Fearon also chaired the
National Institutes of Health and
National Cancer Institute advisory groups and grant review committees. In 2018, Fearon was named a fellow of the
American Association for the Advancement of Science for "distinguished contributions to the cancer field, particularly in defining the role of accumulated mutations in oncogenes and tumor suppressor genes in colon cancer pathogenesis." ==Personal life==