Euphemia, whose name means "honored" was the daughter of
Paul I Mataranga, an
Albanian feudal lord who held the title of
Sevastocrator and ruled the province of Ghora (Gora), situated near
Lake Ohrid. The identity of her mother remains unknown, and not much is known about her early life. She was married to
Andrea II Muzaka most likely around 1328, in the
Church of Saint Anthony in
Durrës. Andrea came from the noble
Muzaka family, and held the titles such as the Despot of Albania, Despot of Epirus and Sebastokrator similar to her father. Through his marriage to Euphemia, Andrea II Muzaka established a significant familial connection with her father, Paul Mataranga, thereby linking the Muzaka and Mataranga families. in
Durrës where Euphemia and her husband Andrea II Muzaka were both married and later buried. Euphemia and her husband, Andrea II Muzaka, were both buried in
Durrës, in the
Church of Saint Anthony where they had previously been married. Their tomb was positioned to the right of the altar. The beautifully crafted marble grave bore an epitaph that read: "Here lies Lord Andrew Molosachi, Despot of Epirus". ==Family==