In 1972, Hussain was appointed
Lecturer of English at the Institute of Education at the University of Sindh, a post she held until 1975. From 1978 to 1988 she taught as lecturer of Sindhi at the University of Karachi. In 1988 she was appointed as assistant professor, a post she held until 1995 when she was appointed a full Professor, and later also chairperson of the department in 1997. In the year 1998, Fahmida Hussain accepted the position of Director, Shah Abdul Latif Bhittai Chair at the University of Karachi. In May 2008, Dr Hussain was appointed to the coveted and prestigious post of chairperson, Sindhi Language Authority. During all these years starting from 1968 to date, Fahmida Hussain has been writing in Sindhi, Urdu and English on various fronts: as a columnist, editor, researcher, translator, author and linguist. Dr Hussain serves as a member on the boards of a number of important educational institutions in the country. Currently she retired from the post of chairperson of Sindhi language Authority (SLA), Sindh. She has also received a number of awards and recognition for her work and contribution. ==Books published==