2013 Friess was a longtime
Republican Party mega-donor, giving millions of dollars to Republican and conservative causes, especially on the
Christian right. Friess donated $250,000 to
Rick Santorum's
re-election campaign in 2006, and at least the same amount to the Republican Governors' Association. Friess largely funded Santorum's unsuccessful campaign for the
2012 Republican presidential nomination. According to campaign filings with the
Federal Election Commission, Friess' contributions to the Red, White and Blue Fund were more than 40% of its total assets, or $331,000 as of December 31, 2011. The million-dollar donation was conveyed in four checks between November 2011 and January 2012. Friess reportedly considered major contributions to
American Crossroads, the super PAC founded by
Republican National Committee chair
Ed Gillespie and
Karl Rove, a former White House strategist for
President George W. Bush . Friess also donated $100,000 to
Wisconsin Governor Scott Walker to help defeat the Democrats'
recall effort in 2011. He reportedly invested more than $3 million in conservative commentator
Tucker Carlson's
The Daily Caller website. While being interviewed by NBC correspondent
Andrea Mitchell regarding
contraception, Friess said, "... this contraceptive thing, my gosh, it's so–it's such–inexpensive, you know, back in my days, they used
Bayer Aspirin for contraception. The gals put it between their knees and it wasn't that costly." Friess later apologized for the comment. Friess was also an advisor to
Turning Point USA, a conservative youth organization to which he donated seed money. In October 2017, he said that he was exploring a possible candidacy for the Senate challenging Wyoming Senator
John Barrasso for the Republican nomination, at the request of
Steve Bannon. However, in April 2018, he instead decided to enter the
crowded Republican field to replace term-limited Governor
Matt Mead. Friess was defeated in the primary, coming in second to State Treasurer
Mark Gordon by 38,951 votes (33%) to 29,842 (25.3%). ==Philanthropy==