Isaac was a founding member and first general coordinator of the
Kefaya opposition group, the movement organised the first protest against Mubarak rule. Isaac was later a member of the
National Association for Change, a
grassroots coalition which prior to the 2011 revolution drew its support from across Egypt’s political spectrum. It was a platform for protest against
Hosni Mubarak’s presidency; political corruption, and stagnation; "the blurring of the lines between power and wealth; and human rights." During the
2012 Egyptian protests, Isaac urged President
Mohamed Morsi to withdraw his constitutional declaration. Isaac was a member of the
National Council for Human Rights. == Death ==