In 1994, de Ferran was invited to test a
CART IndyCar by
Hall/VDS Racing. Despite the worries of the team's sponsor
Pennzoil that de Ferran was not a famous enough name for their car, the team was sufficiently impressed to offer de Ferran a drive for 1995. After dominating the
Cleveland CART PPG Indy Car World Series race he would be taken out while trying to lap
Scott Pruett. He would score his first win in the last race of the year at
Laguna Seca Raceway. After the win, De Ferran placed 14th in the
1995 PPG Indy Car World Series, and won the PPG Indy Car World Series Rookie Of The Year award. This win was also the last for veteran car owner and driver
Jim Hall who retired from the sport at the end of 1996. Hall's retirement also spelled the end of the Jim Hall owned Pennzoil/VDS IndyCar team. He looked on course to win the season opener at
Homestead-Miami Speedway but was knocked out of the lead by
Dennis Vitolo, who was a lap down from de Ferran. At the
Grand Prix of Portland he lost out to
PacWest Racing's
Mark Blundell in the closest finish in CART history. The expected championship challenge never materialized in 1998. Unreliability, driver errors and the inferior performance of the
Goodyear tires compared to the superior
Firestone tires all combined to leave de Ferran 12th in the standings, again with no wins on the year. In 1999, the long-awaited breakthrough finally came as de Ferran beat
Juan Pablo Montoya at
Portland International Raceway to take his first win since 1996 and the
Walker Racing team's first since early 1995. However, after that victory, both Goodyear and
Valvoline left CART as major sponsors and suppliers. Toward the end of that season, de Ferran and
Greg Moore were signed to
Marlboro Team Penske to replace
Al Unser Jr. However, Moore was killed in a crash during the season finale at
California Speedway and de Ferran's fellow countryman
Hélio Castroneves was announced as the replacement for Moore shortly afterwards. On 28 October 2000, during CART qualifying at
California Speedway in
Fontana, de Ferran set both the track record and closed course record for fastest lap at . As of December 2022, this stands as the fastest qualifying lap speed ever recorded at an official race meeting. He would follow the record speed by winning the series championship at Fontana on 30 October (The season finale started on 29 October but was forced to finish on 30 October due to rain). With Team Penske, de Ferran won two
CART titles and an Indy 500 victory. Despite the injury, de Ferran passed his teammate, Castroneves with 31 laps left to win the
2003 Indianapolis 500. It also was the second 1–2 finish for Penske Racing in the Indianapolis 500. Following his Indianapolis triumph, de Ferran decided to retire at the end of 2003. He won his final race at
Texas Motor Speedway, although the moment was soured by a crash during the race that left fellow Indy 500 winner and
Rahal-Letterman Racing driver
Kenny Bräck seriously injured. De Ferran would finish second in the championship standings, runner-up to Scott Dixon. ==Managerial career==