Barcelona in 2008 Born in
Monterrey, Nuevo León, Dos Santos joined
Barcelona's academy of
La Masia at age 13 and played for Barcelona's Juvenil A category, where he helped his team to make a comeback in the league and win the regional title. This title allowed them to participate in the Youth
Copa del Rey, where they faced other regional champions, among them their historic arch-rivals,
Real Madrid. Dos Santos once again played a significant role during the tournament and helped the team win the national title of the Juvenil A category. In 2006, Dos Santos was invited on the pre-season tour of Barcelona's senior squad; during a friendly match on 29 July 2006, he scored in his senior team debut game against Danish club
AGF Aarhus. On 28 November 2006, Barcelona included Dos Santos in their 23-man squad for the
FIFA Club World Cup in Japan. During mid-2007, Dos Santos was once again invited to join Barcelona's senior squad on their pre-season tour. On 29 August 2007, he received dual nationality and was included in the official first team squad. He made his competitive and league debut on 2 September 2007 (at 18 years and 114 days) during a 3–1 home win against
Athletic Bilbao, coming on for
Thierry Henry in the 62nd minute. Dos Santos made his
UEFA Champions League debut on 20 September 2007 during a 3–0 home win against
Lyon. He came on as a substitute for
Xavi in the 79th minute. On 17 May 2008, Dos Santos scored a
hat-trick against
Real Murcia, with a final score of 5–3, granting a victory to Barça on the team's last game of the
2007–08 season. It was also the last game Dos Santos played before joining
Tottenham Hotspur.
Tottenham Hotspur On 18 June 2008, Dos Santos passed a medical and agreed terms to complete his move to Tottenham from Barcelona. Barcelona reported that the transfer fee was €6 million with an additional €5 million payable depending on appearances for Tottenham. Dos Santos was on target twice as Tottenham beat local Spanish side UD Tavernes in 8–0 on their 2008–09 pre-season tour. He also played in Spurs' other pre-season games including the 5–1 wins over
Leyton Orient and
Norwich City. He also scored the second goal in the 3–0 win over
Borussia Dortmund to help Spurs to make it two wins out of two and take home the Feyenoord Jubileum Tournament trophy. He scored his first competitive goal for Spurs in the
UEFA Cup on 26 February 2009 against
Shakhtar Donetsk. After 12 first team appearances, he was sent on loan to
Ipswich Town for the remainder of the season. Dos Santos scored and had an assist in Tottenham's UEFA Europa League group match against
Shamrock Rovers on 29 September 2011 at
White Hart Lane. On 7 January 2012, he scored a goal and completed an assist for a 3–0 win against
Cheltenham Town in the third round of the
FA Cup.
Ipswich Town (loan) In March 2009, Dos Santos signed on loan at
Ipswich Town until the end of the season. He made his debut on 14 March 2009, coming on as a substitute against
Reading. He scored his first league goal and the equaliser in the following game against
Burnley. He scored his second goal against
Bristol City on Easter Monday, a 94th-minute penalty to equalise for Ipswich. He also claimed an assist and a goal from the penalty spot in Ipswich's 3–2 win over local rivals
Norwich City a week later. He finished his loan with four goals in eight appearances. The move reunited the player with
Frank Rijkaard, his former coach at Barcelona. On 31 January, Dos Santos made his debut coming on as a 58th-minute substitute for
Emre Çolak in a
Süper Lig game against
Denizlispor, a 2–1 victory. He returned to Tottenham in the summer having failed to score for Galatasaray, and stayed there for half a season before being loaned to La Liga club
Racing de Santander in January.
Racing Santander (loan) On 31 January 2011, Dos Santos joined La Liga side Racing de Santander on loan until the end of the season from Tottenham. He made his debut for his new club on 5 February 2011 as a substitute against
Real Zaragoza, drawing the game 1–1. He scored his first goal as a substitute against
Villarreal in the 68th minute on 27 February 2011. Dos Santos scored a brace in a 3–2 win league match over
Hércules.
Mallorca midfielder
Hedwiges Maduro It was reported that Dos Santos had told Tottenham that he wanted a move in the summer of 2012 or else he would leave on a free transfer during the next transfer window. His agent stated there was interest from
Serie A club
Inter Milan as well as
Sevilla. On 31 August 2012, Dos Santos signed a four-year deal with Spanish outfit
Mallorca, being introduced as their new number 9. On 22 October, he made his debut for Mallorca, playing 60 minutes and assisting both goals in a 3–2 away defeat to Sevilla. He played another 60 minutes on 28 October in a 5–0 home defeat to Real Madrid. Dos Santos scored his first goal for Mallorca against
Espanyol on 18 January 2013. Though Mallorca would finish the
season in 18th place and was relegated, Dos Santos was a mainstay in the squad, amassing 32 total appearances and finished as their top goal-scorer with six goals as well as seven assists.
Villarreal On 9 July 2013, Dos Santos completed a much speculated move to recently promoted side Villarreal for a reported €6 million. He finished the
2013–14 season with 11 goals and 8 assists, helping the club finish the season in sixth place.
Los Angeles Galaxy On 15 July 2015, the
Major League Soccer club
LA Galaxy announced the signing of dos Santos as a
Designated Player, in a reported US$7 million deal. On 6 August, dos Santos made his competitive debut and scored his first competitive goal for the Galaxy in a
CONCACAF Champions League fixture against Trinidadian side
Central FC. Three days later, he made his MLS debut and scored a goal and provided an assist in the 3–1 win over
Seattle Sounders FC. On October 2, it was reported that dos Santos made
that year's
FIFA Ballon d'Or longlist. In July 2016, dos Santos was included in the roster for the
2016 MLS All-Star Game. On 21 July 2016, he came off of the bench during the quarter-finals of the
U.S. Open Cup, scoring within three minutes of coming onto the pitch. The goal help the Galaxy start a comeback leading to a 4–2 victory over Seattle Sounders to advance to the semi-finals for the first time in ten years. In July 2017, Dos Santos was included in the roster for the
2017 MLS All-Star Game. On 1 March 2019, LA Galaxy announced they had exercised its one offseason buyout of a guaranteed contract on dos Santos, thus releasing him from the team.
Club América On 6 July 2019, Dos Santos officially joined Mexican side
Club América. He played in the
Liga MX for the first time after reaching a three-year agreement with América, being handed the number 10 shirt. In his first
Súper Clasico against
Guadalajara on 28 September, dos Santos suffered a thigh injury following a tackle from
Antonio Briseño, with the defender piercing dos Santos' skin with his studs and leaving a deep gash in his right leg. He was stretchered off the field and immediately taken to a nearby hospital. Club América later released a statement revealing the player had suffered a wound in the quadriceps of the right thigh and would require surgery, thereby ruling him out of action for up to six weeks. On 15 June 2021, Club América released dos Santos. ==International career==