at the
Rochester Institute of Technology As of Jan. 2021, Golisano has pledged or donated more than $300 million to a variety of philanthropic causes. Golisano founded the B. Thomas Golisano Foundation in 1985 with an initial gift of $90,000. The Foundation awards grants to organizations dedicated to providing opportunities for those with intellectual and developmental disabilities and their families. In October 2008, Golisano donated $10 million to
Niagara University for a new B. Thomas Golisano Center for Integrated Sciences building. In November 2009, Golisano donated $4 million to
Ave Maria University for the construction of a new
field house. In 2012, Golisano donated $12 million to the Special Olympics to launch the Healthy Communities initiative. The purpose of the initiative is to increase year-round access to health care for people with intellectual disabilities. He made an additional commitment of $25 million to Special Olympics in 2015 to expand Healthy Communities to 100 locations around the world. This was the largest single gift to an organization made by Golisano and the largest single gifts ever received from an individual by Special Olympics. Also in 2012, Golisano donated $20 million to build a new Golisano Children's Hospital at Lee Health in southwest Florida which opened in Spring 2017. In 2014, the Golisano Neurology and Rehabilitation Center opened at Unity Hospital in Rochester, funded in part by a $10 million contribution from Golisano. Golisano and the Golisano Foundation were recognized among 30 givers and causes on Forbes' "Philanthropy's Big Bets for Social Change of 2015." In June 2016, the Golisano Center for Community Health opened its doors to patients. The center, which provides integrated health care to people with disabilities and their families, was made possible with a gift of $3.5 million from Golisano. In September 2016, Golisano gave $7.5 million to
Nazareth University for a new athletic training center that will aim to be a model of inclusion, fitness and wellness, and is expected to open in 2018. Also in September 2016, Golisano gave $2 million to the
WXXI Public Broadcasting Council for equipment. This was his second gift to WXXI; he gave $2 million in 2004 to allow WXXI to upgrade to digital broadcasting equipment. In April 2017, the City of Rochester announced modified Rochester Broadway Theatre League proposal for
Midtown Plaza which in partnership with Morgan Development would include a performing arts center to be called the Golisano Center for the Performing Arts in honor of a donation made to the project by Golisano. Also in 2017, at the Special Olympics World Games, the first Golisano Global Health Care Leadership Awards were presented to recognize those who are advancing inclusive health for people with intellectual disabilities. Golisano donated $14 million to the
University of Rochester, which renamed their pediatric facility at
Strong Memorial Hospital the
Golisano Children's Hospital in 2002. In 2012, Golisano pledged an additional $20 million to URMC to build a new Golisano Children's Hospital, which opened in 2015. In April 2017, Golisano and the Golisano Foundation pledged $3 million to construct a facility dedicated to providing services to families of autistic children and adults in the city of Rochester. The Golisano Autism Center, which opened in September 2019 in a new 33,000 sq. ft. building, is unique in how it integrated numerous recreational, medical and educational support providers and services into one location. In 2024, Golisano donated $360 million to 82 different non-profits across Upstate New York. In October 2025, Golisano donated $50 million to
UK HealthCare and the
University of Kentucky for naming rights to the Kentucky Children's Hospital, now named
Golisano Children's Hospital at UK. In April 2026, Golisano donated $50 million to
Akron Children's Hospital in
Akron, Ohio, $40 million to
Dayton Children's Hospital in
Dayton, Ohio, and $35 million to
Avera Health in
Sioux Falls, South Dakota, expanding the "Golisano Children’s Alliance hospitals" to 15 locations across the United States. Akron Children's Hospital's Akron campus will be renamed "Akron Children’s, Golisano Campus”; Dayton Children’s Hospital's main campus will be renamed the “Golisano Comprehensive Care Campus”; and Avera Health will name its new children’s hospital, located within the patient care tower at Avera McKennan Hospital & University Health Center, the “Avera Golisano Children’s Hospital." ==Golisano Institute for Business and Entrepreneurship==