Before venturing into politics, Guo has an extensive background as a businesswoman, serving as an incorporator and holding significant shares in at least 11 companies since 2010, according to
Securities and Exchange Commission records. Senator
Win Gatchalian revealed Guo's alleged links with the firm Zun Yuan Technology, Inc., an online casino firm that was registered in the Philippines as a
Philippine Offshore Gaming Operator (POGO). Prior to her election in 2022, In 2019, Baofu Land Development was
incorporated by Guo, Zhang Ruijin, and Lin Baoying, with Rachel Joan Malonzo Carreon and
a Cypriot national, Huang Zhiyang. Furthermore, Guo was reportedly spotted with a
Bulgari Serpenti Viper necklace worth (), a
Louis Vuitton silk shirt, and a
Chanel bag. The POGO hub is situated in the property which is owned by Baofu Land Development, Inc. and is located behind the municipal building in Barangay Anupul, Bamban, and in March 2024, due to allegations of
human trafficking and other
cybercrimes; at that time, it had been renamed Zun Yuan. Meanwhile, Guo countered allegations against her, stating that she was the former landowner of the property, and her vehicle, found within the compound, was sold in 2020. Guo stated that, being one of the incorporators of Baofu, she later sold her shares upon entering politics. Guo stressed that she was "not a coddler, not a protector of POGOs", adding in a subsequent interview by
Karen Davila that she had been rattled by senators' questions about her private life and was opposed to POGOs. On May 16, 2024,
Solicitor General Menardo Guevarra said he designated a "team of solicitors" to investigate if Guo is illegally "holding or exercising a public office" as prefatory to
quo warranto under Rule 66, Revised Rules of Court. On May 23, Senate President
Francis Escudero said that the
burden of proof regarding Guo's citizenship lies upon the accusers. The
Department of the Interior and Local Government , in its updated report submitted on May 17, subsequently recommended that Guo be suspended by the
Ombudsman following what it called "troubling findings" during its investigation over her alleged connections to POGOs. Ombudsman
Samuel Martires, however, told
24 Oras that his office has received the DILG's unsigned
task force's
fact-finding report copy. In effect, the Ombudsman
remanded Guo's case
, hinting that the DILG ought to file a valid criminal
complaint with attached legal documents for Guo's
criminal investigation prior to preventive
suspension. In response, Bamban vice mayor Leonardo Anunciacion said there was no basis for Guo to be suspended, while
Moncada mayor Estelita Aquino, the president of the
League of Municipalities of the Philippines-Tarlac chapter, of which Guo is the treasurer, also defended Guo, saying that she is "helpful and easy to get along with" and that Bamban had progressed under her leadership. The Nationalist People's Coalition also announced an investigation into Guo, with party member Win Gatchalian urging the NPC to expel her. On June 1, the DILG announced that it had filed a criminal complaint to the Ombudsman dated May 24 charging Guo with graft. On June 21, the
Presidential Anti-Organized Crime Commission filed a criminal complaint with the DOJ charging Guo and 13 others with human trafficking involving the POGO in Bamban. On May 21, 2024, Hontiveros, on her social media account, revealed that Guo's business associates, Lin Baoying and Zhang Ruijin, were involved in the
largest money laundering case in
Singapore , amounting to . Guo stated during the Senate hearing later that day that she only found out about her connections to the syndicate after reading Hontiveros' post. Some members of the
House of Representatives also expressed intent to launch a parallel probe of Guo. It also recommended that Guo be temporarily stripped of authority over the Bamban municipal
police force pending her suspension. In response, Guo said that she would not resign and would instead seek reelection as mayor in local elections scheduled in 2025. President
Bongbong Marcos also supported an investigation, adding that she had been under investigation by authorities for some time and that she was not known to most politicians in Tarlac. In an apparent effort to refute Marcos' claims that "no one knows her", photos from Guo's
Facebook and other
social media profiles resurfaced showing both Guo and Marcos together. Photos from March 2022 showed both Guo and Marcos in red shirts and
face masks during the 2022 election campaign, On May 26, 2024,
Chinese-Filipino activist and academic
Teresita Ang See criticized the Senate investigation for focusing too heavily on Guo, claiming that the investigation has been diverted from its main subject of POGOs into an interrogation ofa Guo's lifestyle and ability to speak
Chinese. Ang-See called for the investigation to "focus on the issues that aid legislation", denouncing the current investigation as a "ridiculous tear-jerker '
zarzuela. Guo did not attend the Senate hearings on June 25 and July 10, 2024, citing her physical and mental health. Consequently, she was
subpoenaed by Senator
Risa Hontiveros on June 25 and cited for
contempt by the
Senate Committee on Women, Children, Family Relations and Gender Equality, chaired by Hontiveros, on July 10. On July 11, Guo's assets were ordered frozen by the
Court of Appeals, following a request from the
Anti-Money Laundering Council. On July 12, the Senate released an arrest order for Guo and her alleged relatives over the contempt charges. However, subsequent searches at her possible locations failed to locate her. On August 14, a complaint was filed against Guo by the
Bureau of Internal Revenue for
tax evasion amounting to relating to her transactions in Baofu. On August 30, Guo and 22 others were charged with
money laundering by authorities. On September 5, an arrest warrant was issued by a court in
Capas, Tarlac, against Guo on charges of graft and corruption. After being repatriated from Indonesia, where she had been hiding, Guo reappeared in the Senate hearing on September 9, 2024, but was cited in contempt for a second time by the Senate Committee on Women, Children, Family Relations, and Gender Equality for
perjury and giving evasive answers. In the hearing, it was revealed that Guo was found to have paid Baofu's electric bills totaling when she was mayor from 2022 to 2024. On September 17, the DOJ filed qualified human trafficking charges against Guo and others before the
Pasig Regional Trial Court. On September 19, 2024, Guo appeared in a hearing of the
House of Representatives Quad Committee, a merger of the congressional committees on
dangerous drugs,
public order and safety,
human rights, and
public accounts, as part of its investigation into extrajudicial killings, illegal drugs, and POGOs. She was again cited in contempt for giving evasive answers. On October 3, 2024, the NBI charged Guo with falsification of documents, perjury, and obstruction of justice over her fraudulent signing of legal documents while she was in hiding. On December 12, 2024, the House of Representatives lifted its contempt citation against Guo, citing her custody in separate court cases. On January 15, 2025, Guo and her co-accused were charged with 62 counts of money laundering by the DOJ. On May 23, they were charged with another 62 counts of money laundering by the DOJ. The NBI filed 70 charges against Guo and her relatives on October 2 for falsification of public documents and simulation of minimum capital stock. On November 20, 2025, Guo was convicted of qualified human trafficking, with the sentence being
life imprisonment and a fine of ($33,832). It was a landmark ruling under the Anti-Trafficking in Persons Act, proving that people who are indirectly involved in human trafficking by providing support can be convicted. Guo was moved to the
Correctional Institution for Women. ==Political career==