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Haplogroup E-Z827

E-Z827, also known as E1b1b1b, is a major human Y-chromosome DNA haplogroup. It is the parent lineage to the E-Z830 and E-V257 subclades, and defines their common phylogeny. The former is predominantly found in the Middle East; the latter is most frequently observed in North Africa, with its E-M81 subclade observed among the ancient Guanche natives of the Canary Islands. E-Z827 is also found at lower frequencies in Europe, and in isolated parts of Southeast Africa.

Subclades of E-Z827 and Distribution
Family Tree The following phylogeny is based on the YCC 2008 tree and subsequent published research as summarized by ISOGG. • E-Z827 (Z827) - E1b1b1b • E-V257/L19 (L19, V257) - E1b1b1b1 • E-PF2438 • E-Y10561 • E-FGC18981 • E-FGC38527 • E-Y35933 • E-FGC18960 • E-Y33020 • E-FGC18958 • E-PF2440 • E-PF2471 • E-BY9805 • E-M81 (M81) • E-M81* • E-PF2546 • E-PF2546* • E-CTS12227 • E-MZ11 • E-MZ12 • E-A929 • E-Z5009 • E-Z5009* • E-Z5010 • E-Z5013 • E-Z5013* • E-A1152 • E-A2227 • E-A428 • E-MZ16 • E-PF6794 • E-PF6794* • E-PF6789 • E-MZ21 • E-MZ23 • E-MZ80 • E-A930 • E-Z2198/E-MZ46 • E-A601 • E-L351 • E-Z830 (Z830) - E1b1b1b2 E-PF2431 PF2431 is the sister branch of M81 which was discovered in Paolo Francalacci (2011). Previously, it was designated L19*/V257*. This mutation has been discovered in North Africa (in Souss in Morocco, in central and eastern Algeria, West Nile in Egypt), the Sahel (Chad, Gambia), Western Europe (United Kingdom (Derbyshire), Germany, Switzerland, Spain, Italy) and Near Eastern (Turkey, Karabakh and Urmia). It would have formed 13800 years ago and is thought to originate from the "green" Sahara. Its TMRCA is estimated at 10600 years by yfull. Archeology unearthed the remains of a member of the Hungarian conquering elite was analyzed from branch E-FGC19010, it had been discovered in Sandorfalva in Hungary and is dated to the second half of the tenth century. A skeleton was discovered at the Monastery of San Pietro, Villa Magna in Italy, whose DNA belongs to the same branch and lived around 1180CE. Scientists have examined the DNA of a mass grave of victims of the bubonic plague in Ellwangen in Germany, this one dates from the 16th century and belongs to another branch E-FGC18981. E-M81 E-L19/V257's dominant sub-clade E-M81 is thought to have originated in the Near East of Africa 13,000 years ago and to have been spread by either Phoenicians or by Arabs, or an origin in the area of the northwest of Africa 7,000 years ago, however all Yfull members are M183 and have a TMRCA of just 4200 years ago. E-M81 is the most common subclade of haplogroup E-L19/V257. It is concentrated in MENA, and is dominated by its E-M183 subclade. E-M183 is believed to have originated in the Near East or Northwest of Africa, and has an estimated age of 4200 ybp. The E-M183 sub haplogroup reaches a mean frequency of 42% in North Africa. It decreases in frequency from 100% among some populations to approximately 28.6% to the east of this range in Egypt. The E-M81 subclade is predominant among North-African Berber speaking populations and Maghrebi Arabs. In Tunisia, it reached 100% frequency among a sample of Arabs from Zriba, 89.5% in Andalusians (Qalaat-al-Andalous) and 100% in Berbers from Chenini-Douiret, Jradou and Takrouna. 80% in Mozabite, and 71% in Middle Atlas Berbers (Moyen). It also reaches high levels (77.8%) among the Tuareg population inhabiting the Sahara in Burkina Faso, near Gor it reaches a much lower frequency of 11.1% in the vicinity of Tanut in the Republic of Niger. In this key area from Egypt to the Atlantic Ocean, reports West to East for M183), accompanied by a substantial increasing frequency. At the eastern extreme of this core range, Also found in ifri n'ammar that makes the Northwest African origin the likely origin of where it expanded, and not the Middle East. Europe In Europe, E-M81 has a widespread distribution at very low frequencies but is common mostly in the Iberian Peninsula, where unlike in the rest of Europe, shows an average frequency of 4.3% (49/1140) in the Iberian Peninsula with frequencies reaching 4% and 9% in two separate surveys of Galicia, 10% in Western Andalusia and Northwest Castile. However this study also includes 153 individuals from Majorca, Minorca and Ibiza islands as well as 24 individuals from Gascony which are not in the Iberian Peninsula. Without these 177 individuals, real average for Iberian Peninsula is 4.9% (47/963) to 41% (23/56). E-M81 is also found in other parts of Europe, such as Britain – especially Wales and Scotland – and France, where it has an overall incidence of 2.7% (15/555), with frequencies surpassing 5.0% in Auvergne (5/89) and Île-de-France (5/91). E-M81 was also observed in Italy with frequencies of 0,7% to 5,8% in Sardinia, approximately 2.12% overall in Sicily (but up to 7.14% in Piazza Armerina), and in very much lower frequency near Lucera (1.7%), in continental Italy, possibly due to ancient migrations during the Islamic, Roman, and Carthaginian empires. In a 2014 study by Stefania Sarno et al. with 326 samples from Cosenza, Reggio Calabria, Lecce and five Sicilian provinces, E-M81 shows an average frequency of 1.53%, but the typical Maghrebin core haplotype 13-14-30-24-9-11-13 has been found in only two out of the five E-M81 individuals. These results, along with the negligible contribution from North-African populations revealed by the admixture-like plot analysis, suggest only a marginal impact of trans-Mediterranean gene flows on the current SSI genetic pool. Latin America As a result of Spanish and Portuguese colonization of the Americas, this sub-clade is found throughout Latin America, for example 6.1% in Cuba, (8 out of 132), 5.4% in Brazil (Rio de Janeiro) (6 out of 112), "The presence of chromosomes of North African origin (E3b1b-M81; and among Hispanic men from California and Hawaii 2.4% (7 out of 295), Others In smaller numbers, E-M81 men can be found in areas in contact with the Maghreb, both around the Sahara, in places like Sudan, and around the Mediterranean in places like Lebanon, Turkey, and amongst Sephardic Jews. Distribution The following gives a summary of most of the studies which specifically tested for E-M81, showing where its distribution is greater than 1% in Europe, North Africa, the Middle East and Latin America. E-Z830 (E1b1b1b2) A recently confirmed sub-clade of E-Z827, Z830, includes the confirmed sub-clades of E-M123, E-M293, and E-V42, and is a sibling clade to E-L19. Currently, the E-M35 phylogeny project recognizes four distinct clusters of Z830* carriers, two of which are exclusively Jewish in origin. The remaining two are significantly smaller, and include scattered individuals in Germany, Spain, Latin America, Egypt, and Ethiopia. E-M123 E-M123 is mostly known for its major subclade E-M34, which dominates this clade. E-V1515 A new clade (E-V1515) was defined by Trombetta et al. 2015, which originated about 12 kya (95% CI 8.6-16.4) in eastern Africa where it is currently mainly distributed. This clade includes all the sub-Saharan haplogroups (E-V42, E-M293, E-V92, E-V6) reported as E-M35 basal clades in a previous phylogeny. We observed the highest frequency and diversity of this haplogroup in the northern part of the Horn of Africa (present day Eritrea and northern Ethiopia), where the majority of the deepest E-V1515 subhaplogroups and paragroups were found. In the southern part of the Horn (southern Ethiopia, Somalia and northern Kenya), haplogroup E-V1515 is almost exclusively represented by the recent (3.5 ka; 95% CI: 1.7–5.9 ka) subhaplogroup E-V1486. Further south, in southern Kenya and southern Africa, a single E-V1486 terminal clade, known as E-M293 (Henn et al. 2008), was found (fig. 3). This phylogeographic pattern is strongly suggestive of human movements from the northern part of the Horn to the Ethiopian/Kenyan borders between 12 ka (the coalescence of E-V1515) and 3.5 ka (the coalescence of E-V1486), and from here toward southern Africa across the equatorial belt in more recent times. E-M293 E-M293 is a subclade of E-V1515. It was identified by ISOGG as the second clade within E-Z830. It was discovered before E-Z830 and is associated with the spread of pastoralism from Eastern Africa by South Cushites into Southern Africa. So far high levels have been found in specific ethnic groups in Tanzania and Southern Africa. Highest were the Datog (43%), Khwe (Kxoe) (31%), Burunge (28%), and Sandawe (24%). Two Bantu-speaking Kenyan males were found with the M293 mutation. This is a subclade of E-M293. E-V42 E-V42 was discovered in two Ethiopian Jews. E-V6 The E-V6 subclade of E-V1515 is defined by V6 and has been identified a significant presence of these lineages in Ethiopia, and also some in the neighboring Somali population. Among the Ethiopian and Somali samples, the highest were 14.7% among the Ethiopian Amhara, and 16.7% among the Ethiopian Wolayta. E-V92 E-V92 was discovered in two Ethiopian Amhara. Like E-V6 and E-V42 it possibly only exists in the area of Ethiopia. ==Phylogenetics==
Phylogenetics
Phylogenetic History Prior to 2002, there were in academic literature at least seven naming systems for the Y-Chromosome Phylogenetic tree. This led to considerable confusion. In 2002, the major research groups came together and formed the Y-Chromosome Consortium (YCC). They published a joint paper that created a single new tree that all agreed to use. Later, a group of citizen scientists with an interest in population genetics and genetic genealogy formed a working group to create an amateur tree aiming at being above all timely. The table below brings together all of these works at the point of the landmark 2002 YCC Tree. This allows a researcher reviewing older published literature to quickly move between nomenclatures. Original Research Publications The following research teams per their publications were represented in the creation of the YCC Tree. == See also ==
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