Southern section The southern portion is a southwest–northeast road in
Floyd and
Harrison counties. Its southern terminus is at
State Road 135 near the town of
Mauckport, which is on the
Ohio River. From there, the highway runs roughly northeast for a distance of about and ends where it meets
State Road 62, east of the town of
Lanesville.
Northern section The northern portion is a north–south road in
Bartholomew and
Jackson counties. Its southern terminus is at
State Road 250 in the small town of
Dudleytown a few miles south of
Seymour; the highway runs north through Seymour to
Columbus, a distance of about , and ends where it meets
Indiana State Road 46. == History ==