Sequeira married Esther d'Aguilar (1739-1791), the daughter of
Baron Diego Pereira d'Aguilar. In
Jews and Medicine: An Epic Saga, Frank Heynick describes him as "wealthy and pompous". His descendants include Jane Sequeira, a British doctor married to the financier
Jonathan Ruffer, who collects Spanish old masters and Gainsborough paintings. ==References==