Brereton unsuccessfully contested
Stoke-on-Trent Central in a by-election on 23 February 2017, finishing third. He attracted some negative publicity for a mailshot his campaign released which contained false claims about two local Labour MPs voting against the then Prime Minister
Theresa May's
Brexit withdrawal agreement and for a poster that misspelled Brexit. After the Government announced that there would be a General Election taking place in June 2017, the
Conservative Campaign Headquarters told the local
Conservative Association to choose Brereton from a list of one, after he was promoted by his boss, the Cabinet Minister
Karen Bradley. This was at the expense of Joe Rich, who had added four per cent to the Conservative Party vote share when he stood in the constituency in the
2015 general election and had hoped to stand again. Brereton went on to defeat the sitting Labour MP
Rob Flello and take the seat on 9 June 2017, making him the first Conservative to win in the constituency in over 80 years. Aged 26, he was the youngest Conservative MP in the 2017 intake. In September 2018 he was appointed as the
Parliamentary Private Secretary to the
Department for Education. Following his election as MP for Stoke South, Brereton continued with his role on the city council until June 2019 when he did not stand for re-election. He was the Parliamentary Private Secretary to the
Department for Exiting the European Union between September 2019 and 31 January 2020. Following the closure of the Department for Exiting the European Union, Brereton was appointed as the Parliamentary Private Secretary to the
Secretary of State for Defence. Brereton resigned his position as Parliamentary Private Secretary to the
Secretary of State for International Trade on 7 July 2022 as part of the
July 2022 United Kingdom government crisis, one of the last to do so before
Boris Johnson announced his resignation as party leader. Brereton lost his seat during the
2024 general election to
Labour challenger
Allison Gardner.
European Union Brereton is a supporter of
Brexit, saying he is "optimistic about our future in leaving the EU". In February 2019 he labelled the behaviour of
European Union officials as "threatening and aggressive". ==Post-parliamentary career==