In 1857, he moved to
Portland, Oregon, where he was well received by the medical community, and soon acquired a large private practice. In 1858, he took charge of the county hospital under a contract from
Multnomah County, subsequently establishing a private hospital for the insane. The hospital was so successful that the state government, during
Governor Whiteaker's term in 1862, contracted with him to assume the care of the insane of Oregon. Assisted by Dr. A. M. Loryea, this grew into
Oregon Hospital for the Insane. This contract was from time to time renewed by the
State Legislature, and until his death Hawthorne had charge as Superintendent and Physician of the unfortunate wards of the state, which at the time of his death numbered some 500 inmates. Hawthorne was known for his kindness toward his patients and his devotion to his work. During the 21 years that he had charge of the Oregon Hospital for the Insane, it became widely known and was regarded as one of the best institutions of its kind in the United States. Hawthorne was highly proficient in every department of his profession and is highly honored by the record he made as authority upon diseases of the mind. He gained national renown in the treatment of insanity, and the curative rate of his institution was considered equal to that of any similar establishment in the United States. Hawthorne took an active interest in public affairs. Politically, he was originally a Whig, but after the overthrow of that party he became a Democrat. He commanded respect from members of both parties, and he was retained in office for many years when the state was under
Republican rule. He declined to become a candidate for high public stations. He was a
Christian, and for many years was a consistent member of the
Episcopal Church. He was a productive and highly regarded man at the time of his death. ==Family and later life==