The second son of
George Skene (1736–1776) of
Rubislaw, Aberdeen, and his wife Jane (Jean) Moir of Stoneywood, he was born at Rubislaw on 7 March 1775. In 1783 Jane, George Skene’s widow, moved to Edinburgh for the education of her seven children. James Skene attended
Edinburgh high school. An elder brother died in 1791, and James became heir of Rubislaw. At 21 he went to Germany as a student, and, returning to Edinburgh, was admitted to the
Scottish bar as an advocate in 1797. His friendship with
Sir Walter Scott was built on his knowledge of German literature. In 1797 Skene became cornet of the
Edinburgh Light Horse, the regiment largely organised by Scott, who was himself its quartermaster, secretary, and paymaster. In 1817 he was elected a Fellow of the
Royal Society of Edinburgh. His proposers were Sir
George Steuart Mackenzie,
Thomas Charles Hope, and Sir
David Brewster. From 1820 to 1834 he was the Curator of its library and museum. He was active in the
Scottish Society of Antiquaries. By 1820 he left his brother's house and obtained a house at 126
Princes Street facing
Edinburgh Castle. By this stage he was also actively practising as an advocate. By 1830 he was living in a magnificent house at 46 Moray Place on the
Moray Estate in west Edinburgh. For the health of his family, Skene went to Greece in 1838, staying for several years near Athens, in a villa built to his own design. Returning in 1844, he lived first at
Leamington Spa and then at Frewen Hall, Oxford, where he died on 27 November 1864. ==Works and legacy==