Television and film career Keddie had guest roles early in her career in various television dramas, including her first roles in
Five Mile Creek (1985),
Fortress (1986) and
Janus (1994). She played the role of Marriane Sheridan in
Blue Heelers (season 3, episode 21) airing on 18 June 1996 and
Good Guys, Bad Guys (1997). From 1997 to 1998, she came to the attention of senior network television producers, appearing in
State Coroner. Following this, she had a recurring role in
Stingers from 2000 to 2004. Keddie's big break came in 2004, where she had a leading role in
Love My Way, a drama series airing on Foxtel. The series ended in late 2007. This role led to Keddie being nominated for various awards for playing the part of Julia Jackson, a woman who struggles to cope with her own identity in the midst of family tragedy. Keddie's award win came at the end of
Love My Way third series in 2006. In 2009, Keddie appeared in three different roles. She portrayed police officer Liz Cruickshank in the television drama
Underbelly: A Tale of Two Cities and journalist Jacinta Burns, in the TV series
Rush, as well as Dr Carol Frost in
X-Men Origins: Wolverine. In 2010, Keddie depicted author
Blanche d'Alpuget in
Hawke, a telemovie about the premiership of
Bob Hawke (the
Prime Minister of Australia, 1983–91). She also became the star of the drama series
Offspring, which began airing in August 2010. In April 2011, she had the leading role of
Ita Buttrose in
ABC1's telemovie
Paper Giants: The Birth of Cleo, the story of Buttrose's rise to success as the editor of
Cleo magazine. In 2014, Keddie starred in
Party Tricks as Premier Kate Ballard. Ballard faces an election campaign alongside newly announced Opposition candidate David McLeod (
Rodger Corser), with whom she once had a tumultuous affair. In 2019, Keddie starred in the ABC1 acclaimed series "
The Cry". In March 2020, she starred in a 6 part series on ABC1, "
Stateless". The series also stars and is produced by Australian actress,
Cate Blanchett and is set in a detention centre in the middle of the Australian outback. In 2021, Keddie played Heather Marconi in the
Nicole Kidman led
Hulu series
Nine Perfect Strangers alongside
Melissa McCarthy,
Samara Weaving and
Bobby Cannavale. In 2023, Keddie portrayed Evelyn Jones in
Strife and in August 2024, it was announced she would be returning for a second season. On 31 August, Keddie was named in the cast of ABC series
Plum. In 2024, Keddie was nominated for a
Gold Logie during the
2024 Logie awards.
Stage Making her theatre debut for the
Melbourne Theatre Company in 1998 in
Patrick Marber's
Closer, Keddie went on to appear in
Cyrano de Bergerac,
Les Liaisons dangereuses,
Birthrights,
Great Expectations,
The Seagull and
Hannie Rayson's
Life After George. Her performances in the 2005 Melbourne Theatre Company production of
Les Liaisons dangereuses, and the Playbox's
The Ishmael Club, both earned her
Green Room Award nominations. In 2007 Keddie starred alongside Jay Bowen in the Melbourne Theatre Company's play
The Glass Soldier written by
Hannie Rayson. ==Personal life==