1991–99: Beginnings and Clueless Sisto made his film debut in the 1991 drama
Grand Canyon, starring
Kevin Kline and
Steve Martin. He followed this with roles in the television films
Desperate Choices: To Save My Child (1992) and
The Shaggy Dog (1994). In his early film and television career, Sisto played a killer in
Hideaway (1995); a rich teen in
Clueless (1995); a 20-something kidnapper in
Suicide Kings (1997); Olympic gold medalist long-distance runner
Frank Shorter in
Without Limits (1998);
Jesus Christ in the
CBS miniseries
Jesus (1999); and a widowed filmmaker in
This Space Between Us (1999). He has also starred in the films
Moonlight and Valentino (1995),
White Squall (1996),
Bongwater (1997),
Some Girl (1998), and
Playing by Heart (1998). In 1996, Sisto screen tested for the character of Jack Dawson in the
James Cameron film
Titanic alongside
Kate Winslet but ultimately lost out on the role to
Leonardo DiCaprio. In 1998, he portrayed
Frederick W. Seward in the
TNT television film
The Day Lincoln Was Shot.
2000–10: Six Feet Under and Law & Order From 2001 to 2005, he portrayed
Billy Chenowith in the
HBO drama series
Six Feet Under. For that work, he was twice nominated for the
Screen Actors Guild Award for Outstanding Performance by an Ensemble in a Drama Series along with his co-stars. Sisto starred in the 2001 drama film
Angel Eyes, alongside
Jennifer Lopez. In 2003, Sisto starred in the drama film
Thirteen, the romantic comedy
The Movie Hero, and the horror film
Wrong Turn. That same year, he also appeared in the series finale of
The WB's teen drama series ''
Dawson's Creek''. Sisto then performed on the Los Angeles stage, playing the role of bigoted Southerner Shane Mungitt in
Richard Greenberg's play
Take Me Out, about a baseball player who announces he is gay; Sisto was nominated for a Los Angeles Drama Critics Circle Award for his role. In 2006, he appeared in the
Broadway play
Festen at the
Music Box Theatre. In the same year, he starred in the short-lived
NBC drama series
Kidnapped, top-lined the direct-to-video mystery horror film
Population 436, and starred in the crime-thriller film
Unknown. In July 2007, Sisto was featured in the
Maroon 5 video for the song "
Wake Up Call". He played a man who was sleeping with the girlfriend of
Adam Levine. That same year, he appeared as Earl Hunterson opposite
Keri Russell in the comedy-drama film
Waitress. In 2008, Sisto joined the cast of the
NBC crime drama series
Law & Order, as Detective
Cyrus Lupo, replacing
Milena Govich's Detective Nina Cassady as the partner of
Jesse L. Martin's
Ed Green. Sisto had already appeared on the show, as a lawyer, in the previous season's finale. Sisto stayed on for the series' next three seasons, and his character became partners with
Anthony Anderson's Detective
Kevin Bernard after Martin left the series near the end of season 18. Also in 2008, Sisto starred in the drama film
Gardens of the Night, and voiced the role of
Batman in the
direct-to-video film
Justice League: The New Frontier. In 2009, he played a Catholic priest, alongside
Kristin Chenoweth as a prostitute, in the independent drama film
Into Temptation. The following year, he starred in the
Manhattan Theatre Club production of
Spirit Control at the
New York City Center, gaining rave reviews for his performance as Adam Wyatt.
2011–present: Suburgatory, screenwriting debut and FBI From 2011 to 2014, Sisto starred in the
ABC comedy series
Suburgatory, which premiered on September 28, 2011. He played the role of George Altman, the divorced father of the series' main character, for three seasons, after which the series was cancelled. Sisto was nominated for the 2013
Critics' Choice Television Award for Best Actor in a Comedy Series for his performance as George. In 2011, he starred in the drama film
Sironia, directed by
Brandon Dickerson. In 2012, he starred as Sheriff Rowlings in the critically acclaimed science-fiction comedy-drama
Robot & Frank. The following year, Sisto co-starred as Guy Karlsburg, alongside
James Marsden and
Claire Danes, in the comedy-drama
As Cool as I Am. In 2014, Sisto co-wrote the screenplay for the comedy film
Break Point with Gene Hong. He also starred in the film and served as a producer. On June 5, 2014, it was announced that Sisto had joined the cast of
Carlton Cuse's remake of
The Returned for the cable channel
A&E. The series lasted one season before it was cancelled by the network. He then voiced
Talon in the animated direct-to-video film
Batman vs. Robin. In 2015, Sisto produced and starred as Aaron Miller in the British thriller film
Hangman, which had its premiere at
South by Southwest. That same year, he joined the cast of ABC's crime drama series
Wicked City. Sisto portrayed Detective Jack Roth, an LAPD officer searching for a serial killer on the Sunset Strip. The role was originally portrayed by
Adam Rothenberg, but after the series was given its premiere date, the role was recast. It was poorly received by critics and was cancelled by ABC after airing only three episodes following weak ratings. Sisto was then cast alongside
Archie Panjabi in ABC's drama pilot
The Jury, but the project was not picked up to series. From 2016 to 2018, Sisto starred as Freddy Green in
Antoine Fuqua's
Audience Network drama series
Ice, opposite
Cam Gigandet and
Donald Sutherland. Sisto currently portrays Assistant Special Agent-in-Charge Jubal Valentine in
Dick Wolf's
CBS drama series
FBI. == Personal life ==