Born in
Logan, West Virginia, Dru moved to New York City in 1940 at the age of eighteen. After finding employment as a model, she was chosen by
Al Jolson to appear in the cast of his
Broadway show
Hold On to Your Hats. When she moved to
Hollywood, she found work in the
theater. Dru was spotted by a talent scout and made her first film appearance in ''
Abie's Irish Rose'' (1946). Over the next decade, Dru appeared frequently in films and on television. She was often cast in
western films such as
Howard Hawks's
Red River (1948), and the
John Ford productions
She Wore a Yellow Ribbon (1949), and
Wagon Master (1950). She gave a well-received performance in the dramatic film ''
All the King's Men'' (1949), which went on to win the Academy Award for Best Picture, played a college graduate turned gangster's unhappy
moll opposite
Edmund O'Brien in the crime
noir 711 Ocean Drive (1950), and co-starred with
Dan Dailey in
The Pride of St. Louis (1952), about major-league baseball pitcher
Jerome "Dizzy" Dean. She appeared in the
James Stewart drama
Thunder Bay in 1953 and then the
Martin and Lewis comedy
3 Ring Circus (1954). Her film career lessened by the end of the 1950s, but she continued working frequently in television, most notably as Babs Hooten on the 1960–61
ABC sitcom,
Guestward, Ho! After
Guestward, Ho!, she appeared sporadically for the rest of the 1960s and the first half of the 1970s, with one feature film appearance, in
Sylvia (1965), and eight television appearances. For her contribution to the television industry, Dru was awarded a star on the
Hollywood Walk of Fame. ==Personal life==