Culpepper married and had children, including: • John Alexander Culpeper (December 9, 1800, Anson County, North Carolina, United States of America – March 26, 1873, Darlington County, South Carolina, US); became a pastor. His first wife was "Let." (Leticia?) Russell. He secondly married Catherine Pinkney (December 8, 1807, North Carolina, US – December 11, 1883, Society Hill, Darlington County, South Carolina, US). His children included: • Dr. James Furman Culpeper (July 11, 1834, Anson County, North Carolina, US – June 24, 1917, Timmonsville, Florence County, South Carolina, US). His son by his first wife "Let." Russell. Captain of Culpepper's South Carolina Battery (SC 3rd Palmetto Battalion, Light Artillery Company C) during the
American Civil War, thereafter a medical doctor for 50 years. • A. Fuller Culpeper (June 28, 1843, Darlington County, North Carolina – Dade County, Florida). His son by either his first or second wife. Fuller through battlefield promotions eventually became a lieutenant in his elder brother's light artillery battery. • Charles M Culpeper (May 23, 1845, Darlington County, North Carolina – May 9, 1860 (aged 14)). Son by his second wife Catherine Pinkney. • Evan Alexander Culpepper Sr. (March 17, 1808, Anson County, North Carolina, United States of America – June 10, 1884, Coryell County, Texas, United States of America); had issue. ==Death==