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Joseph G. Gleeson

Joseph Gleeson is an American physician-scientist and professor of neurosciences and genetics at University of California, San Diego (UCSD). He is known for his research on the genetic and molecular mechanisms underlying neurodevelopmental disorders, including structural birth defects, epileptic encephalopathies, and spina bifida.

Early life and education
Gleeson earned his M.D. from Pritzker School of Medicine at the University of Chicago in 1991, and completed his residency in pediatrics and neurology and fellowship in neurogenetics at Boston Children's Hospital and Harvard Medical School. There, in the laboratory of Christopher A. Walsh, he identified the doublecortin gene as the cause for X-linked lissencephaly and double cortex syndrome, a form of pachygyria, later showing that the gene encodes a Microtubule-associated protein. == Career ==
Career
Gleeson joined the faculty at the University of California, San Diego in 1999, later moving to a position within Howard Hughes Medical Institute and Rockefeller University, but eventually returning to UCSD, where he serves as the Rady Distinguished Professor of Neurosciences and Pediatrics, as Director of Neurosciences at Rady Children's Hospital Institute for Genomic Medicine, and as Chief Medical Officer of the n-Lorem Foundation. with genomic technologies such as whole-genome sequencing and mosaic variant barcode analysis. ==Research==
Research
Gleeson's research addresses: • Mosaic genetic mutations and their role in structural birth defects • Multi-omics approaches in patient-derived neurons for therapeutic discovery ==Selected publications==
Selected publications
• • • • • • • • ==Awards and honors==
Awards and honors
Gleeson has been recognized for his work through several awards and honors, which include: • John Merck Program in the Developmental Disabilities in Childhood • Klingenstein Award in the Neurosciences • Ray Thomas Edwards Foundation Award • HHMI Investigator • Searle Scholar • Member of the National Academy of Medicine • Sachs Scientific Achievement Award ==See also==
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