Sonnabend was one of the first physicians to notice among his gay male patients the immune deficiency that would later be named AIDS. His background in
microbiology,
virology, infectious diseases This suggestion conflicted with the view that a single agent was likely responsible, which Sonnabend did not rule out. Sonnabend's "multifactorial model" led him to argue from very early in the emerging pandemic that frequent unprotected
anal sex increased the risk of what would come to be known as AIDS. This was the inspiration for
How to Have Sex in an Epidemic, At the time, attempts to change
sexual behaviour and the recommendation of condoms for gay sex met with criticism from many prominent
gay community figures.
Role in founding AIDS organisations To help fund his research and that of other scientists—and because the
CDC were dismissive of his expertise and uninterested in his assistance Sonnabend served as medical director of CRI/CRIA until 1996. Dr Krim described that "he's the only doctor I know who goes to every funeral". This
non-profit organisation was the first and largest formally recognised
AIDS buyers' club, ==Controversies==