. Remulla made a comeback in politics in 2010, when he ran for governor. In the race, he defeated Vice Governor Dencito Campaña, who had the backing of Maliksi. Under his tenure, Cavite was cited as one of the top-performing provinces in the Philippines by the
Department of the Interior and Local Government (DILG). Also, it is the first and only province to be
ISO 9001:2008 certified. In the
2013 elections, Remulla sought a second term as governor, with actor and Cavite Liga ng mga Barangay (League of Barangays) President
Jolo Revilla, son of Senator
Bong Revilla and Representative
Lani Mercado, as his running mate. Maliksi challenged him in the race. During the campaign, Remulla accused Maliksi of being involved in the anomalous
LRT extension project, where ₱500 million (about US$11.162 million) was allotted for 2,000 housing units, road, lighting and water projects, relocation sites and payments for the residents directly affected by the development. Remulla even threatened to resign if his allegations are proven wrong. And he said
Mas mabuti ang mamigay, wag lang magnakaw () Despite most surveys showing Maliksi would beat him by a wide margin, Remulla went on to win the election by more than 50,000 votes. Jolo Revilla also won, beating Maliksi's running mate, Ronald Jay Lacson, son of Senator
Panfilo Lacson. He was named as one of
People Asia magazine's "People of the Year" in 2013, along with
Megan Young, who won
Miss World 2013. In 2014, Remulla was assigned by Vice President
Jejomar Binay as his new spokesperson. Remulla was supposed to run for his last term as governor in
2016 but he decided to quit as Binay asked him to become
secretary of the interior and local government should Binay win the presidency. He also cited plans to pursue postgraduate studies as a reason for retiring from the governorship. His brother,
Jesus Crispin, ran in his stead and later won. However, as of April 29, 2016, Remulla was confirmed to have left Binay's camp in support of presidential candidate
Rodrigo Duterte. Remulla successfully sought a comeback as governor in
2019, defeating former Governor Maliksi for the second time. He sought re-election
2022 and won, this time with
Tagaytay councilor
Athena Tolentino, the daughter of 8th district representative
Abraham Tolentino, as his running mate. He also supported the successful
campaign of presidential candidate
Bongbong Marcos and vice-presidential candidate
Sara Duterte. == Secretary of Interior and Local Government (2024–present) ==