Early appearances Squibb worked at
The Muny and trained with
HB Studio. In 1951, she moved to Cleveland to sing and dance at the
Cleveland Play House and starred in productions such as
Marseilles, ''
The Play's the Thing, Goodbye, My Fancy, The Heiress
, Detective Story
, Antigone
, Ladies in Retirement
and Bloomer Girl
. In the late 1950s, she and her second husband, Charles Kakatsakis, moved to New York City to pursue careers on Broadway. She played Dulcie in the 1958 off-Broadway The Boy Friend and starred in the 1959 Off-Broadway revival of Lend an Ear. She replaced Electra for her Broadway debut in the original production of Gypsy: A Musical Fable. Squibb appeared in the 1968 Broadway version of The Happy Time. The musical was nominated for the Tony Award for Best Musical. She did modeling work for romance novels, and performed on road tours and cruise ships, and worked as Santa Claus’s helper at Christmas in the shopping malls. After this role, she appeared in films Far from Heaven (2002), Welcome to Mooseport (2004), and Just Add Water (2008). From 2005 to 2007, she had a recurring role in the CBS crime series Ghost Whisperer, and from 2008 to 2009 played Pearl on the CBS soap opera, The Young and the Restless. She also appeared in the made-for-television films A Stranger's Heart (2007) and Shark Swarm (2008) and guest-starred on The Middle, Castle and Mike & Molly. In 2011, she played Stella Gordon in Dividing the Estate'' at the Dallas Theater Center and received standout reviews.
Breakthrough In 2013, Squibb starred opposite
Bruce Dern in the road comedy-drama film
Nebraska, directed by
Alexander Payne. She received positive reviews for her performance. Film critic
Christy Lemire from
RogerEbert.com called her a "scene-stealer", while
Peter Travers from the
Rolling Stone called her "priceless". She received
Boston Society of Film Critics Award for Best Supporting Actress and
Satellite Award for Best Supporting Actress – Motion Picture, as well as being nominated for an
Academy Award for Best Supporting Actress, a
Golden Globe Award for Best Supporting Actress – Motion Picture, the
Screen Actors Guild Award for Outstanding Performance by a Female Actor in a Supporting Role and the
Independent Spirit Award for Best Supporting Female among other accolades for the film. Following her big break, Squibb guest-starred on
Girls,
Glee,
Devious Maids,
Mom and
Getting On. She was inducted into the Cleveland Play House Hall of Fame in 2016. In 2015, Squibb starred opposite
Blythe Danner in the comedy-drama film ''
I'll See You in My Dreams. Later that year, she appeared in the Christmas comedy-drama Love the Coopers. In 2016, she guest-starred on The Big Bang Theory'' as Sheldon's meemaw. Later that year, she had a recurring role as Etta Teasdale in the Showtime comedy-drama series
Shameless. In 2017, she guest-starred alongside
Hal Holbrook on ''
Grey's Anatomy. She also appeared in the films Other People (2016), Father Figures (2017), Blow the Man Down (2019), Palm Springs (2020), Hubie Halloween (2020), The Humans (2021) and Family Squares (2022). She played Old Josie in the 2018 Broadway production of Waitress. She had a supporting role in the Disney+ fantasy film Godmothered in 2020. She played Vivian, the grandmother of Eddie Palmer (Justin Timberlake), in Apple TV+ 2021 film Palmer. From 2018 to 2019, she had a recurring role in the NBC crime comedy-drama Good Girls. She also played Mrs. Danforth, a rich benefactor, in "The Indoor Arm", the final episode of the second season of the Apple TV+ series Little America''. In 2024, Squibb had a first leading role in the action comedy film,
Thelma. It received mostly positive reviews from critics. Mae Abdulbaki wrote in her
Screen Rant review: "June Squibb proves she's still on top of her acting game in an energetic, charming adventure comedy that is actually genuinely funny." That same year, she appeared in the black comedy ''
Don't Tell Mom the Babysitter's Dead''. Squibb starred in another leading role in
Scarlett Johansson's directorial debut film
Eleanor the Great. ==Acting credits==