Early years (2021–2024) monument in Karachi is featured on the club crest The club was formed in 2021 by football coach
Adeel Rizki, along with businessman and co-founder Shahzaib Ahmed Khan in Karachi. Primarily focused on grassroots football development, the club rapidly emerged as one of the top talent-nurturing academies in Pakistan. After the appointment of Rizki as coach of the
Pakistan women's national team in 2022, most of the club players featured internationally. In April 2024,
futsal section secured the Women's Futsal Championship title after an 11–0 victory over the city rivals
Karachi United.
Top-flight (2024–present) Karachi City won the title their first participation at the top-tier women competition at the
2024 National Women Football Championship. The team included several notable international players such as
Zulfia Nazir, and several overseas players including
Nadia Khan and
Zahmena Malik. In their next match, the club hammered Mohsen Gillani WFC by 33–0. The win resulted in Karachi City winning their three-team group with 6 points and a staggering +77 goal difference in two matches. After several goal dominated wins, the team reached the semifinals, consequently winning against Hazara Quetta by 8–0. The team clinched the title after winning against
Legacy WFC by 4–0.
British Pakistani Nadia Khan was declared player of the tournament, along with Nisha Ashraf who was awarded the best goalkeeper. ==Crest and colors==