Main •
Matthew Rhys as
Perry Mason, a low-rent private investigator who later becomes a lawyer •
Juliet Rylance as
Della Street, the loyal and driven legal secretary of E.B. Jonathan •
Chris Chalk as
Paul Drake, a
beat cop with a knack for detective work •
Shea Whigham as Peter "Pete" Strickland (season 1; recurring season 2), Mason's work partner •
Tatiana Maslany as Sister Alice McKeegan (season 1), a preacher and leader of the Radiant Assembly of God •
John Lithgow as Elias Birchard "E.B." Jonathan (season 1), a struggling attorney and regular employer of Perry Mason •
Justin Kirk as
Hamilton Burger (season 2; recurring season 1), assistant district attorney offering Mason legal advice •
Diarra Kilpatrick as Clara Drake (season 2; recurring season 1), Paul's wife •
Eric Lange as Eugene "Gene" Holcomb (season 2; recurring season 1), an LAPD homicide detective •
Katherine Waterston as Virginia "Ginny" Aimes (née Szymanski) (season 2), an optimistic schoolteacher of Perry's son, Theodore ("Teddy")
Recurring •
Verónica Falcón as Lupe Gibbs, an accomplished pilot and the owner of a
speakeasy who has a sexual relationship with Mason •
Molly Ephraim as Hazel Prystock, a hand model who is Della's fellow boarding house tenant and secret romantic partner •
Gretchen Mol as Linda Mason, Perry's ex-wife
Season 1 •
Gayle Rankin as Emily Dodson, the mother of Charlie Dodson, a one-year-old child who is mysteriously kidnapped and murdered •
Nate Corddry as Matthew Dodson, a grocery store owner whose one-year-old son, Charlie, is kidnapped and murdered •
Jefferson Mays as Virgil Sheets, an attendant at the city morgue and a friend of Mason's •
Stephen Root as Maynard Barnes, the formidable
district attorney of Los Angeles County •
Andrew Howard as Joseph "Joe" Ennis, an LAPD homicide detective •
Robert Patrick as Herman Baggerly, Matthew's father, a powerful industrialist in Southern California who hires E.B. and Mason to investigate the kidnapping •
Lili Taylor as Birdy McKeegan, Alice's mother and advisor •
Matt Frewer as Judge Frederick "Fred" Wright, the judge in the Charlie Dodson murder case •
David Wilson Barnes as Elder Ethan Brown, a member of the Radiant Assembly of God •
Taylor Nichols as Elder/Deacon Eric Q. Seidel, a member of the Radiant Assembly of God •
Aaron Stanford as George "Pinky Ring" Gannon, a man with a critical connection to the Dodson case •
Jenny O'Hara as June Pitlick, the owner of the boarding house where Della Street lives •
Michael McMillian as Oliver Fogg, one of Della's fellow lodgers • Todd Weeks as James "Jim" Hicks, an accountant who worked for George Gannon and others •
Andrew Divoff as Al Howard, the owner of the casino where George Gannon worked
Season 2 •
Tommy Dewey as Brooks McCutcheon, a wealthy oil scion and a philanthropist with a darker side who aspires to bring a baseball team to Los Angeles •
Paul Raci as Lydell McCutcheon, Brooks' father, a ruthless businessman who succeeded his empire to his son • Kersti Bryan as Elizabeth McCutcheon, Brooks' widow •
Jee Young Han as Marion Kang, Mason's new secretary •
Sean Astin as Sunny Gryce, a dueling supermarket owner Mason represents •
Jen Tullock as Anita St. Pierre, a self-made screenwriter Della meets and is attracted to •
Mark O'Brien as Thomas Milligan, Hamilton Burger's deputy in charge of the Brooks McCutcheon murder case • Onohoua Rodriguez as Luisa Gallardo, the aunt of the Gallardo brothers who are accused of murdering Brooks McCutcheon • Fabrizio Guido as Rafael Gallardo, an 18-year-old Mexican-American artist accused of murdering McCutcheon • Peter Mendoza as Mateo Gallardo, Rafael's unemployed 20-year-old elder brother and an aspiring mechanic, also accused of murdering McCutcheon • Stephanie Hoston as Sofia Gallardo, Mateo's wife and the mother of the couple's young daughter Maria •
Hope Davis as Camilla Nygaard, the rival of the McCutcheon family in the oil business • Danielle Gross as Noreen Lawson, Brooks' former flame • Andrea Gabriel as Constance Barbour, a gifted pianist once taught by Camilla •
Wallace Langham as Melville Phipps, a Los Angeles native and the attorney of Camilla Nygaard •
Tom Amandes as Judge Durkin, the Gallardo trial judge • Jon Chaffin as Morris, Clara's brother and Paul's brother-in-law •
John DiMaggio as "Fighting" Frank Finnerty, a conservative radio personality on Lydell McCutcheon's payroll ==Episodes==