Main •
Satomi Ishihara as Misaki Fukazawa / Misaki Sakuraba • Honma Aizaki as young Misaki Fukazawa :27 years old. Hazuki's younger sister. She is sloppy in relationships with men, and her room is messy and untidy. Having crushed every milestone in her sister's life, she ends up at her sister's house, whom she hasn't seen in years, with a certain goal to achieve. When she was in high school, she had a platonic male friend Soichiro with whom she reunited a few years later. She had one relationship and became pregnant. After she became pregnant, she thought about the baby in her womb, and despite working at a cabaret club, she refrained from drinking. She confesses to her best friend Nagano that Soichiro is the father of her child, and she has a disease called systemic lupus erythematosus. After she loses consciousness due to symptoms of the disease, Hazuki and Nanae find out about the disease she had hidden until then. She later marries Eito. Her condition worsens during her pregnancy, and she gives birth by caesarean section. She names her child Hana. •
Nao Matsushita as Hazuki Fukazawa / Hazuki Hagiwara • Runa Ozawa as young Hazuki Fukazawa :29 years old. Misaki's older sister. She is a service staff at Ward Office Citizens' Life Department Citizen Service Department; she later becomes wedding dress studio Ryo's apprentice designer. She excels at advancing things systematically and has a methodical personality. Ever since she was a child, she has been embroiled in troubles caused by her sister, and her peaceful life is completely changed when her sister, who is a troublemaker, appears again. She lost her father when she was young, but it was because her father had an accident on the way to go shopping for Hazuki. However, her mother Nanae did not tell Hazuki the truth, and she has kept it hidden until now. She is shocked when he hears about Misaki's pregnancy from Soichiro but is purely happy that her sister will have a child. Learning of her sister's illness, she vows to never let Misaki die and announces to her family that she will marry Yohei.
Fukazawa family •
Nagisa Katahira as Nanae Fukazawa :55 years old. Mother of Hazuki and Misaki. • Otomo Noa as Hana Sakuraba :Misaki's daughter with Soichiro. Her stepfather is Eito, who is also her uncle.
Related to the Fukazawa family •
Takanori Iwata as Eito Sakuraba :27 years old. Misaki's best friend. He is called Hachi by Misaki because his name is Eito which sounds like Eight in English. Misaki thought he was gay, but in fact he was just lying to build a good friendship with Misaki. He proposed to Misaki, whom he had been in love with since the day they met, and they later got married. •
Seiichi Tanabe as Soichiro Sakuraba :42 years old. Hidemitsu seminar lecturer. Hazuki's former high school homeroom teacher. Father of Misaki's child, Hana. The school and parents found out about his sleepover with Masaki, and he had to resign from the high school he worked at. After that, he worked as a cram teacher in Shizuoka, but came back to Tokyo due to personnel changes. He ignored Masaki, who contacted him many times, for her sake. He had one romantic relationship, with Misaki, whom he met for the first time in many years, but that caused Misaki to become pregnant. He still likes Misaki, and really wants to date her. •
Kanna Mori as Kazuko Sato :30 years old. Hazuki's best friend.
Ward office •
Yuta Hiraoka as Tatsuya Yoshimura :30 years old. Hazuki's ex-fiancée. Health Insurance Division employee. Due to Misaki's influence, his relationship with Hazuki breaks down. •
Megumi Yamano as Naoko Hirayasu :32 years old. A colleague of Hazuki. Every time she opens her mouth, she says to Hazuki that she is offended, and enjoys annoying her. There is some useful information in it.
APPLESEED •
Hiroyuki Hirayama as Yohei Hagiwara :36 years old. Kaori's younger brother. His regular customer Hazuki, who visits him at lunch, is a favorite of his, and he cherishes her; they eventually get married. • Keiko Horiuchi as Kaori Uesugi :40 years old. Yohei's older sister. She is married, has three sons and works. • Kento Muto as Souta :Employee. • Kyoichi Mikuriya as Shunsuke :Employee. • Sou Yamanaka as Naohisa Uesugi :Kaori's husband. • Kishou Inoue as Kagetora Uesugi :Eldest son of the Uesugi family. The son of Naohisa and Kaori. • Riku Oonishi as Masatora Uesugi :Second son of the Uesugi family. • Rento Ooyama as Terutora Uesugi. :Third son of the Uesugi family. • Ryusei Ota as Kenshin Uesugi :Fourth son of the Uesugi family. He is the same age as Hana, daughter of Misaki and Eito.
Other •
Rina Aizawa as Machiko • Ayai Sato as Hitomi • Risako Tanigawa as Yuko
Cameos Episode 1 •
Miyuu Sawai as Rio :Newlywed couple. • Hideaki Kabumoto as Kento :Newlywed couple.
Episode 2 •
Hiroyuki Watanabe as Shinji Shibukawa :Nanae's fiancé. •
Yasuyuki Maekawa as Ryutaro Shimizu :Cabaret club customer, Yokohama Chuo University Hospital physician. • Shinnosuke Yokotsuka as Hiroshi :Cabaret clubber wearing black clothes. • Kinya Kikuchi as Saionji :Cabaret club customer, Saionji Construction president
Episode 3 • Yujiro Kazama as Hikaru • Kinari Hirano as Yuta
Episode 5 • Satomi Nagano as Takahashi :Obstetrician, gynecologist, Misaki's doctor.
Episode 6 • Kyouko Yanagihara as Kyoko :Apparel shop owner, Misaki's employer. •
Hayato Onozuka as Shiraishi :Eito's college friend
Episode 7 •
Koutaro Tanaka as Hirose :Kazuko's matchmaking partner. • Shige Uchida as Tsuchida :Kazuko's work colleague, Hirose's friend. • Yuuta Tanokura as Yoshiki :Lawyer, Eito's college friend.
Episode 8 •
Kazuma Suzuki as Ryo Shibata :Wedding dress designer, Hazuki's employer. • Kei Okotsuki as Takako Aso :Soichiro's ex-wife. • Daisuke Yamazaki as Iwamoto :Collagen disease physician, Misaki's doctor. • Yukiko Shinohara as Reika :Wedding dress workshop craftsman.
Episode 9 •
NAOTO as Kuwana :Eijin's senior, professional skateboarder.
Episode 10 • Kouji Shimizu as Eiichiro Sakuraba :Soichiro and Eito's father. • Rumi Maruyama as Satoko Sakuraba :Soichiro and Eito's stepmother. ==References==